Research Advances in the Correlation between Peroxisome Proliferator-Activated Receptor- and Digestive Cancers.

Peroxisome proliferator-activated receptor- (PPAR) is a class of ligand-activated nuclear transcription factors, which is a member of type II nuclear receptor superfamily. Previous studies demonstrate that PPAR is expressed in a variety of tumor tissues and is closely associated with the proliferation and prognosis of digestive system tumors by its roles in mediation of cell differentiation, induction of cell apoptosis, and inhibition of cell proliferation.