Dogiparthi S N, Muralidhar K, Seshadri K G, Rangarajan S
Department of Dermatology, Venereology and Leprosy, Department of Endocrinology, Diabetes and Metabolism, Sri Ramachandra Medical College and Research Institute, Porur, Chennai, Tamilnadu, India.
Dermatoendocrinol. 2017 Dec 6;9(1):e1395537. doi: 10.1080/19381980.2017.1395537. eCollection 2017.
There is a rise in number of people diagnosed with Diabetes Mellitus. The incidence is rising in modern Indian society because of Industrial development and drastically changing lifestyles. Diabetic neuropathies are microvascular disorders that are usually associated with the duration of Diabetes. Among the various forms, the most common is Diabetic Peripheral Neuropathy. The disease if neglected leads to chronic ulcer formation leading to amputations frequently. Hence the aim of this study is to document the early cutaneous changes and create an early awareness in the importance of controlling Diabetes. The study consisted of 205 patients with Type 2 DM. Participant's neuropathy status was determined based on Neuropathy Disability Score and Diabetic Neuropathy Symptom Score. Among the Skin changes documented, the common changes seen were: Peripheral hair loss in 185 (90.2%), Xerosis in 168 (82%), Anhydrosis in 162 (79%), Plantar Fissures in 136 (66.3%), Plantar Ulcer in 80 (39%), common nail changes documented were Onychomycosis in 165 (80.5%) and Onychauxis in 53 (25.8%) patients in relation to the occupation and duration of Diabetes mellitus. In conclusion, it is important to control glycemic levels in the all stages of Diabetes and institute foot care measures to prevent the complications of neuropathy.
被诊断患有糖尿病的人数在增加。由于工业发展和生活方式的急剧变化,现代印度社会中糖尿病的发病率正在上升。糖尿病神经病变是通常与糖尿病病程相关的微血管疾病。在各种形式中,最常见的是糖尿病周围神经病变。如果忽视这种疾病,会导致慢性溃疡形成,常常导致截肢。因此,本研究的目的是记录早期皮肤变化,并让人们尽早认识到控制糖尿病的重要性。该研究包括205名2型糖尿病患者。根据神经病变残疾评分和糖尿病神经病变症状评分来确定参与者的神经病变状态。在记录的皮肤变化中,常见的变化有:185例(90.2%)出现周围性脱发,168例(82%)出现皮肤干燥,162例(79%)出现无汗,136例(66.3%)出现足底皲裂,80例(39%)出现足底溃疡,记录的常见指甲变化有165例(80.5%)出现甲癣和53例(25.8%)出现甲肥厚,这些变化与糖尿病患者的职业和病程有关。总之,在糖尿病的各个阶段控制血糖水平并采取足部护理措施以预防神经病变并发症很重要。