Seyis Sabri
Department of Cardiology, Liv Hospital, Istinye University, Istanbul, Turkey.
Cardiol Res Pract. 2018 Feb 1;2018:2451581. doi: 10.1155/2018/2451581. eCollection 2018.
Coronary slow flow is a rare, clinically important entity observed in acute coronary syndrome. The pathophysiological mechanism is not fully elucidated. We investigated patients with chest pain who had angiographic features consistent with the coronary slow flow. One hundred ten patients were included. Electrocardiography, echocardiography, and angiography results were retrospectively noted. The mean age was 56.4. Fifty-eight were male, and fifty-two were female. The control group consisted of patients with normal angiography. Patients had higher diastolic blood pressure, lower mean ejection fraction, higher average left ventricular end-diastolic diameter, and higher mean left atrial size than the control group (=0.009, =0.017, =0.041, and < 0.001, resp.). Patients had higher average V1 ID, V6 ID, P wave dispersion, TFC LAD, TFC Cx, TFC RCA, and TFC levels than the control group. A significant linear positive relationship was found between the V1 ID and the TFC LAD, TFC Cx, TFC RCA, and TFC; also between the V6 ID and the TFC LAD, TFC Cx, TFC RCA, and TFC. Angiographic and electrocardiographic features are suggestive and diagnostic for the coronary slow flow syndrome. Although when regarded as a benign condition, coronary slow flow should be diagnosed, followed up, and treated as many of laboratory features suggest ischemic events.
冠状动脉慢血流是在急性冠状动脉综合征中观察到的一种罕见但具有临床重要性的情况。其病理生理机制尚未完全阐明。我们对具有与冠状动脉慢血流一致的血管造影特征的胸痛患者进行了研究。共纳入110例患者。回顾性记录了心电图、超声心动图和血管造影结果。平均年龄为56.4岁。男性58例,女性52例。对照组由血管造影正常的患者组成。与对照组相比,患者的舒张压更高、平均射血分数更低、平均左心室舒张末期直径更大、平均左心房大小更大(分别为=0.009、=0.017、=0.041和<0.001)。患者的平均V1 ID、V6 ID、P波离散度、TFC LAD、TFC Cx、TFC RCA和TFC水平高于对照组。发现V1 ID与TFC LAD、TFC Cx、TFC RCA和TFC之间存在显著的线性正相关;V6 ID与TFC LAD、TFC Cx、TFC RCA和TFC之间也存在显著的线性正相关。血管造影和心电图特征对冠状动脉慢血流综合征具有提示和诊断作用。尽管冠状动脉慢血流被视为一种良性情况,但鉴于许多实验室特征提示存在缺血事件,仍应进行诊断、随访和治疗。