Ülker Volkan, Atalay Hasan Anıl, Çakır Çağlar, Sargan Aytül
Clinic of Urology, Okmeydanı Training and Research Hospital, İstanbul, Turkey.
Clinic of Pathology, Okmeydanı Training and Research Hospital, İstanbul, Turkey.
Turk J Urol. 2018 Jan;44(1):79-81. doi: 10.5152/tud.2017.39039. Epub 2017 Dec 19.
We present a case of malignant fibrous histiocytoma of the testis in a 59 year- old male who admitted to our hospital with left testicular painless mass presenting for two months. A scrotal ultrasound examination and magnetic resonance imaging revealed a 9 cm left testicular solid mass. Serum tumor markers were unremarkable. The patient underwent left radical orchiectomy. Histopathologic diagnosis was giant cell variant of malignant fibrous histiocytoma which composed of varying amounts of a mixture of spindled, rounded and osteoclastic type giant cells. Hemorrhagic and necrotic areas were seen between tumor nodules. In immunohystochemical staining, vimentin, CD68 were positive and SMA was focally positive. The patient then received adjuvant chemoterapy and currently, he has no sign of recurrence.
我们报告一例59岁男性睾丸恶性纤维组织细胞瘤,该患者因左侧睾丸无痛性肿块两个月入院。阴囊超声检查和磁共振成像显示左侧睾丸有一个9厘米的实性肿块。血清肿瘤标志物无异常。患者接受了左侧根治性睾丸切除术。组织病理学诊断为恶性纤维组织细胞瘤的巨细胞变型,由不同数量的梭形、圆形和破骨细胞型巨细胞混合组成。肿瘤结节间可见出血和坏死区域。免疫组织化学染色显示,波形蛋白、CD68阳性,平滑肌肌动蛋白局灶性阳性。患者随后接受了辅助化疗,目前无复发迹象。