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ImmPort,旨在重新利用开放获取的免疫学检测数据,用于转化和临床研究。

ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.

机构信息

Institute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.

Northrop Grumman Health Solutions, Rockville, MD 20850, USA.

出版信息

Sci Data. 2018 Feb 27;5:180015. doi: 10.1038/sdata.2018.15.

DOI:10.1038/sdata.2018.15
PMID:29485622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5827693/
Abstract

Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components-Private Data, Shared Data, Data Analysis, and Resources-for data archiving, dissemination, analyses, and reuse. To date, more than 300 studies have been made freely available through the Shared Data portal (www.immport.org/immport-open), which allows research data to be repurposed to accelerate the translation of new insights into discoveries.

摘要

免疫学家开始探索可重复性、免疫数据再利用和二次分析的可能性。开放获取数据集正被应用于验证原始研究中使用的方法,利用这些研究进行荟萃分析,或产生新的假设。为了促进这些目标,ImmPort 数据存储库为更广泛的研究社区创建,以探索广泛的临床和基础研究数据及相关发现。ImmPort 生态系统由四个组件组成——私有数据、共享数据、数据分析和资源,用于数据归档、传播、分析和再利用。迄今为止,通过 Shared Data 门户(www.immport.org/immport-open)免费提供了 300 多项研究,这允许重新利用研究数据,以加速将新见解转化为发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/7693c4ba70d5/sdata201815-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/7e6bce3bc61a/sdata201815-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/656ef6f4993c/sdata201815-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/70b820329d2a/sdata201815-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/7693c4ba70d5/sdata201815-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/7e6bce3bc61a/sdata201815-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/656ef6f4993c/sdata201815-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/70b820329d2a/sdata201815-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/103c/5827693/7693c4ba70d5/sdata201815-f4.jpg

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