Topić Berislav, Mašić Tarik, Radović Svjetlana, Lincender Ivor, Muhić Edin
Academy of Sciences and Arts of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina.
Clinical Department of Maxillofacial Surgery, Sarajevo University Hospital Centre, University of Sarajevo.
Acta Clin Croat. 2017 Jun;56(2):323-330. doi: 10.20471/acc.2017.56.02.17.
Oral melanoma (OM) occurs from activated or genetically altered epidermal melanocytes. There is no scientific evidence that OM can be linked to physical, chemical and thermal irritation, or to other risk factors of the oral cavity. According to fi gures from various countries, OM accounts for 0.2% to 7.5% ( Japan) of all cases of melanoma of the skin and mucous membrane. The male to female ratio of OM is 2:1. About 80% of OMs are located in the mucosa of the palate and maxillary gingiva. This paper presents two cases of oral mucosal melanoma of the upper and lower lips in women aged 62 and 59 years. Diagnosis, differential diagnosis and therapy are reported.
口腔黑色素瘤（OM）由活化或基因改变的表皮黑素细胞发生。没有科学证据表明OM可与物理、化学和热刺激或口腔的其他危险因素相关联。根据各国数据，OM占皮肤和黏膜黑色素瘤所有病例的0.2%至7.5%（日本）。OM的男女比例为2:1。约80%的OM位于腭部和上颌牙龈黏膜。本文介绍了两例分别为62岁和59岁女性上下唇口腔黏膜黑色素瘤的病例。报告了诊断、鉴别诊断及治疗情况。
