使用胶原-糖胺聚糖基质修复青光眼引流装置暴露后的结膜
Conjunctival repair after glaucoma drainage device exposure using collagen-glycosaminoglycane matrices.
作者信息
Rosentreter André, Lappas Alexandra, Widder Randolf Alexander, Alnawaiseh Maged, Dietlein Thomas Stefan
机构信息
Department of Ophthalmology, University of Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany.
Center of Ophthalmology, University of Cologne, Cologne, Germany.
出版信息
BMC Ophthalmol. 2018 Feb 27;18(1):60. doi: 10.1186/s12886-018-0721-6.
BACKGROUND
To report the results of the repair of conjunctival erosions resulting from glaucoma drainage device surgery using collagen-glycosaminoglycane matrices (CGM).
METHODS
Case series of 8 patients who underwent revision surgery due to conjunctival defects with exposed tubes through necrosis of the overlying scleral flap and conjunctiva after Baerveldt drainage device surgery. The defects were repaired by lateral displacement of the tube towards the sclera, with a slice of a CGM as a patch, covered by adjacent conjunctiva.
RESULT
Successful, lasting closure (follow-up of 12 to 42 months) of the conjunctival defects was achieved without any side-effects or complications in all eight cases.
CONCLUSIONS
Erosion of the drainage tube, creating buttonholes in the conjunctiva after implantation of glaucoma drainage devices, is a potentially serious problem. It can be managed successfully using a biodegradable CGM as a patch.
背景
报告使用胶原-糖胺聚糖基质（CGM）修复青光眼引流装置手术导致的结膜糜烂的结果。
方法
对8例患者进行病例系列研究，这些患者在Baerveldt引流装置手术后，因覆盖巩膜瓣和结膜坏死致引流管暴露，结膜出现缺损而接受翻修手术。通过将引流管向巩膜侧移位，并使用一片CGM作为补片，然后用相邻结膜覆盖来修复缺损。
结果
所有8例患者均成功实现结膜缺损的持久闭合（随访12至42个月），且无任何副作用或并发症。
结论
青光眼引流装置植入后，引流管糜烂导致结膜出现扣眼是一个潜在的严重问题。使用可生物降解的CGM作为补片可成功解决该问题。
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