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[营养不良:从发病机制到当前的诊断与治疗方法]

[Malnutrition: from pathogenesis to current methods for diagnosis and treatment].

作者信息

Kostyukevich O I, Sviridov S V, Rylova A K, Rylova N V, Korsunskaya M I, Kolesnikova E A

机构信息

N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow, Russia.

出版信息

Ter Arkh. 2017;89(12. Vyp. 2):216-225. doi: 10.17116/terarkh20178912216-225.

Abstract

Progressive weight loss is a frequent companion to somatic pathology. The risk of death is known to increase dramatically among those with a body mass index of less than 19 kg/m. Even mild weight loss in the presence of severe diseases can have a substantial impact on the course of the disease. The paper presents current views on malnutrition, its prevalence in the presence of various somatic diseases, and clinical significance. It describes the basic pathogenetic components of weight loss and the possible ways of correcting nutritional status. Particular emphasis is placed on the methods of nutritional support that is currently regarded as one of the most important components of a comprehensive approach to treating patients with chronic diseases. The authors give recommendations for the assessment of the nutritional status of patients in clinical practice and algorithms for their malnutrition management.

摘要

进行性体重减轻常伴随躯体疾病出现。已知体重指数低于19kg/m的人群死亡风险会急剧增加。即使在患有严重疾病时出现轻度体重减轻,也会对疾病进程产生重大影响。本文介绍了关于营养不良的当前观点、其在各种躯体疾病中的患病率以及临床意义。它描述了体重减轻的基本发病机制组成部分以及纠正营养状况的可能方法。特别强调了营养支持方法,目前该方法被视为慢性病患者综合治疗方法中最重要的组成部分之一。作者给出了临床实践中评估患者营养状况的建议以及营养不良管理算法。

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