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调节对苦味酸氯接触敏感性的抑制性T传入细胞可跨越遗传屏障发挥作用。

T suppressor afferent cells which regulate contact sensitivity to picryl chloride act across genetic barrier.

作者信息

Dieli F, Abrignani S, Salerno A

出版信息

Immunol Lett. 1986 Nov 17;14(1):49-52. doi: 10.1016/0165-2478(86)90019-2.

DOI:10.1016/0165-2478(86)90019-2
PMID:2948907
Abstract

This paper investigates the requirement for genetic restriction in the action of T suppressor afferent cells (Ts-aff) which regulate the induction phase of contact sensitivity to picryl chloride. The results here reported show that Ts-aff which inhibit both the induction of contact sensitivity and DNA synthesis in the draining lymph nodes of sensitized mice, act across both H-2 and Igh genetic barrier and constitute new evidence which discriminates between two T suppressor cell populations in contact sensitivity.

摘要

本文研究了调节对苦味酸氯接触敏感性诱导期的抑制性T传入细胞(Ts-aff)作用中遗传限制的必要性。此处报告的结果表明,抑制致敏小鼠引流淋巴结中接触敏感性诱导和DNA合成的Ts-aff可跨越H-2和Igh遗传屏障发挥作用,并构成了区分接触敏感性中两个抑制性T细胞群体的新证据。

相似文献

1
T suppressor afferent cells which regulate contact sensitivity to picryl chloride act across genetic barrier.调节对苦味酸氯接触敏感性的抑制性T传入细胞可跨越遗传屏障发挥作用。
Immunol Lett. 1986 Nov 17;14(1):49-52. doi: 10.1016/0165-2478(86)90019-2.
2
Infection of mice with Newcastle disease virus inhibits the T suppressor afferent cell circuit which regulates contact sensitivity to picryl chloride.用新城疫病毒感染小鼠会抑制调节对苦味酸氯接触敏感性的T抑制传入细胞回路。
Cell Immunol. 1985 Aug;94(1):225-30. doi: 10.1016/0008-8749(85)90099-1.
3
Suppression of contact sensitivity to picryl chloride. Interaction between T suppressor auxiliary cells, suppressor factors and macrophages.对苦味酸氯的接触敏感性抑制。T抑制辅助细胞、抑制因子与巨噬细胞之间的相互作用。
Arch Immunol Ther Exp (Warsz). 1983;31(6):849-55.
4
Suppressor cells for the afferent phase of contact sensitivity to picryl chloride: inhibition of DNA synthesis induced by T cells from mice injected with picryl sulfonic acid.对苦味酸氯接触敏感性传入相的抑制细胞:对注射苦味酸磺酸的小鼠T细胞诱导的DNA合成的抑制
J Immunol. 1979 Jun;122(6):2300-3.
5
Regulatory responses in contact sensitivity: afferent suppressor T cells inhibit the activation of efferent suppressor T cells.
Cell Immunol. 1991 Feb;132(2):400-10. doi: 10.1016/0008-8749(91)90037-c.
6
Suppressor T cell circuits in contact sensitivity. I. Two mechanistically distinct waves of suppressor T cells occur in mice tolerized with syngeneic DNP-modified lymphoid cells.接触敏感性中的抑制性T细胞回路。I. 在同基因二硝基苯(DNP)修饰的淋巴细胞诱导耐受的小鼠中出现两批机制不同的抑制性T细胞。
J Immunol. 1982 Aug;129(2):461-8.
7
Aclacinomycin-A inhibits the development and the expression of suppressor cell activity to contact sensitivity.阿克拉霉素 A 抑制接触敏感性抑制细胞活性的发展和表达。
Immunopharmacology. 1985 Aug;10(1):19-25. doi: 10.1016/0162-3109(85)90055-4.
8
Role of the fourth complement component (C4) in the regulation of contact sensitivity. I. Analysis in mice with high and low C4 levels.第四补体成分(C4)在接触敏感性调节中的作用。I. 对C4水平高和低的小鼠的分析。
Cell Immunol. 1987 Apr 1;105(2):386-96. doi: 10.1016/0008-8749(87)90086-4.
9
Effect of the H-2 and Igh complexes on the susceptibility to ultraviolet B-induced immunosuppression in murine contact sensitivity and contact photosensitivity.H-2和Igh复合体对小鼠接触性敏感和接触性光敏感中紫外线B诱导的免疫抑制易感性的影响。
Photodermatol Photoimmunol Photomed. 1990 Apr;7(2):73-6.
10
Induction of contact sensitivity. Selective induction of delayed hypersensitivity by the injection of cells from draining lymph nodes into the footpads of normal recipients.接触敏感性的诱导。通过将引流淋巴结中的细胞注射到正常受体的足垫中,选择性诱导迟发型超敏反应。
Immunology. 1978 Apr;34(4):725-31.

引用本文的文献

1
Regulation of lymphocyte proliferation in contact sensitivity: homeostatic mechanisms and a possible explanation of antigenic competition.接触敏感性中淋巴细胞增殖的调节:稳态机制及对抗原竞争的一种可能解释。
Immunology. 1989 Apr;66(4):577-82.