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低速追尾志愿者研究的综合回顾及与实际结果的比较。

A Comprehensive Review of Low-Speed Rear Impact Volunteer Studies and a Comparison to Real-World Outcomes.

机构信息

Biodynamic Research Corporation, San Antonio, TX.

出版信息

Spine (Phila Pa 1976). 2018 Sep 15;43(18):1250-1258. doi: 10.1097/BRS.0000000000002622.

Abstract

STUDY DESIGN

This study combined all prior research involving human volunteers in low-speed rear-end impacts and performed a comparative analysis of real-world crashes using the National Automotive Sampling System - Crashworthiness Data System.

OBJECTIVE

The aim of this study was to assess the rates of neck pain between volunteer and real-world collisions as well as the likelihood of an injury beyond symptoms as a function of impact severity and occupant characteristics in real-world collisions.

SUMMARY OF BACKGROUND DATA

A total of 51 human volunteer studies were identified that produced a dataset of 1984 volunteer impacts along with a separate dataset of 515,601 weighted occupants in real-world rear impacts.

METHODS

Operating-characteristic curves were created to assess the utility of the volunteer dataset in making predictions regarding the overall population. Change in speed or delta-V was used to model the likelihood of reporting symptoms in both real-world and volunteer exposures and more severe injuries using real-world data. Logistic regression models were created for the volunteer data and survey techniques were used to analyze the weighted sampling scheme with the National Automotive Sampling System database.

RESULTS

Symptom reporting rates were not different between males and females and were nearly identical between laboratory and real-world exposures. The minimal risk of injury predicted by real-world exposure is consistent with the statistical power of the large number of volunteer studies without any injury beyond the reporting of neck pain.

CONCLUSION

This study shows that volunteer studies do not under-report symptoms and are sufficient in number to conclude that the risk of injury beyond neck strain under similar conditions is essentially zero. The real-world injury analyses demonstrate that rear impacts do not produce meaningful risks of cervical injury at impacts of similar and greater severity to those of the volunteer research. Future work concerning the mechanism of whiplash-related trauma should focus on impacts of severity greater than those in the current literature.

LEVEL OF EVIDENCE

摘要

研究设计

本研究综合了所有涉及低速追尾事故中人类志愿者的先前研究,并使用国家汽车抽样系统-碰撞安全数据系统(NASS-CDS)对真实世界中的事故进行了对比分析。

研究目的

本研究旨在评估志愿者和真实世界碰撞中颈部疼痛的发生率,以及作为碰撞严重程度和乘员特征函数的损伤超出症状的可能性。

背景资料概要

共确定了 51 项人类志愿者研究,这些研究产生了一个包含 1984 次志愿者碰撞的数据集,以及一个包含 515601 名真实世界后碰撞加权乘员的独立数据集。

方法

创建了操作特征曲线,以评估志愿者数据集在对总体人群进行预测方面的效用。使用速度变化或 delta-V 来模拟真实世界和志愿者暴露中报告症状的可能性,以及使用真实世界数据来模拟更严重的损伤。为志愿者数据创建了逻辑回归模型,并使用调查技术对国家汽车抽样系统数据库中的加权抽样方案进行了分析。

结果

症状报告率在男性和女性之间没有差异,在实验室和真实世界暴露之间几乎相同。真实世界暴露预测的最小损伤风险与大量志愿者研究的统计能力一致,这些研究没有任何除颈部疼痛报告之外的损伤。

结论

本研究表明,志愿者研究没有报告症状不足的情况,并且数量足够多,可以得出结论,在类似条件下,颈部拉伤以外的损伤风险基本为零。真实世界的损伤分析表明,在后碰撞中,不会产生与志愿者研究相似或更严重的碰撞严重程度下有意义的颈椎损伤风险。未来与挥鞭伤相关创伤机制有关的工作应侧重于比目前文献中更严重的损伤。

证据水平

3 级

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76c9/6203429/14187e371897/brs-43-1250-g002.jpg

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