Ding Wei, Tan Yulin, Xue Wenbo, Wang Yibo, Xu Xue-Zhong
Department of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou, Jiangsu Province, China.
Medicine (Baltimore). 2018 Mar;97(9):e0063. doi: 10.1097/MD.0000000000010063.
The conventional Billroth I anastomosis (cBIA) after laparoscopic distal gastrectomy (LDG) is performed through circular staple extracorporeally. Now, delta-shaped anastomosis (DA), which is performed using a linear stapler intracorporeally, becomes popular. We conducted a meta-analysis to compare the effectiveness and safety between the 2 techniques.
A systematic literature search was performed using PubMed, Ovid, and the Cochrane Library Central. Participants of any age and sex, who underwent DA, or cBIA after LDG, were considered following inclusion criteria.
A total of 11 articles, published between 2010 and 2017, fulfilled the selection criteria. The total sample size of these studies was 2729 cases, including DA group 1008 cases and cBIA group 1721 cases. Compared to cBIA group, patients in DA group had less blood loss (mean deviation [MD] = -0.68, 95% confidence interval [CI] = -0.15 to -0.31, P < .001), fewer administration of analgesics (MD = -0.82, 95% CI = -1.58 to -0.05, P = .04), lower NRS score on POD 1 (MD = -0.84, 95% CI = -1.34 to -0.33, P = .001), lower NRS score on POD 3 (MD = -0.38, 95% CI = -0.50 to -0.26, P < .001). Furthermore, compared to cBIA group, obese patients in DA group had fewer total number of complications (MD = 0.46, 95% CI = 0.22 to 0.95, P = .04), shorter postoperative hospital stays (MD = -0.73, 95% CI = -1.18 to -0.28, P = .001), earlier first flatus (MD = -0.30, 95% CI = -0.50 to -0.10, P = .004), fewer administration of analgesics (MD = -1.08, 95% CI = -1.61 to -0.55, P < .001), lower NRS score on POD 1 (MD = -0.68, 95% CI = -0.99 to -0.37, P < .001) and lower NRS score on POD 3 (MD = -0.63, 95% CI = -0.86 to -0.40, P < .001).
Compared with cBIA, DA is a safe and feasible procedure, with similar surgical outcomes and postoperative complications. In terms of postoperative recovery, DA is less invasive with quicker resume than cBIA, especially for the obese patients.
腹腔镜远端胃切除术后的传统毕罗一式吻合术(cBIA)是通过体外圆形吻合器完成的。现在,使用体内线性吻合器进行的三角形吻合术(DA)越来越受欢迎。我们进行了一项荟萃分析,以比较这两种技术的有效性和安全性。
使用PubMed、Ovid和Cochrane图书馆中心进行系统的文献检索。符合纳入标准的是任何年龄和性别的参与者,他们在腹腔镜远端胃切除术后接受了DA或cBIA。
2010年至2017年间发表的11篇文章符合选择标准。这些研究的总样本量为2729例,其中DA组1008例,cBIA组1721例。与cBIA组相比,DA组患者的失血量更少(平均偏差[MD]=-0.68,95%置信区间[CI]=-0.15至-0.31,P<0.001),镇痛药物使用量更少(MD=-0.82,95%CI=-1.58至-0.05,P=0.04),术后第1天的数字疼痛评分量表(NRS)得分更低(MD=-0.84,95%CI=-1.34至-0.33,P=0.001),术后第3天的NRS得分更低(MD=-0.38,95%CI=-0.50至-0.26,P<0.001)。此外,与cBIA组相比,DA组肥胖患者的并发症总数更少(MD=0.46,95%CI=0.22至0.95,P=0.04),术后住院时间更短(MD=-0.73,95%CI=-1.18至-0.28,P=0.001),首次排气更早(MD=-0.30,95%CI=-0.50至-0.10,P=0.004),镇痛药物使用量更少(MD=-1.08,95%CI=-1.61至-0.55,P<0.001),术后第1天的NRS得分更低(MD=-0.68,95%CI=-0.99至-0.37,P<0.001),术后第3天的NRS得分更低(MD=-0.63,95%CI=-0.86至-0.40,P<0.001)。
与cBIA相比,DA是一种安全可行的手术方法,手术效果和术后并发症相似。在术后恢复方面,DA的创伤较小,恢复速度比cBIA更快,尤其是对于肥胖患者。