Ivanova V V, Govorova L V, Gudieva N B, Lukina V V, Bulovskaia L N
Vopr Med Khim. 1986 Nov-Dec;32(6):111-5.
Content of total lipids, intensity of lipid peroxidation and activity of ATPases were studied in lymphocytes of children with acute respiratory-viral infection (ARVI). Decrease in the content of total lipids correlated with lipid peroxidation in ARVI. At the same time, a decrease in the activity of ATPases occurred due to a decrease in the content of total lipids and alteration in the phospholipid composition of lymphocyte membranes. At the period of convalescence the patterns studied tended to normalization only in children with non-complicated forms of ARVI. Active and slowly-developed lipid peroxidation in lymphocytes of various children groups suggest dissimilar alterations in the structure and composition of the cellular membranes, which increases our knowledge on pathogenesis of ARVI.
对患有急性呼吸道病毒感染（ARVI）的儿童淋巴细胞中的总脂质含量、脂质过氧化强度和ATP酶活性进行了研究。ARVI中总脂质含量的降低与脂质过氧化相关。同时，由于总脂质含量的降低以及淋巴细胞膜磷脂组成的改变，ATP酶活性出现下降。在恢复期，只有患有非复杂性ARVI形式的儿童中所研究的各项指标趋于正常。不同儿童组淋巴细胞中活跃且缓慢发展的脂质过氧化表明细胞膜的结构和组成存在不同改变，这增加了我们对ARVI发病机制的认识。
