Helen DeVos Children's Hospital Health Weight Center, Grand Rapids, Mich; Department of Kinesiology, Michigan State University, East Lansing, Mich; Diabetes Institute, Ohio University, Athens, Ohio; Department of Family Medicine, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio.
Helen DeVos Children's Hospital Health Weight Center, Grand Rapids, Mich; Department of Pediatrics, Michigan State University, East Lansing, Mich; USA Football, Indianapolis, Ind.
Acad Pediatr. 2018 Jul;18(5):589-592. doi: 10.1016/j.acap.2018.02.011. Epub 2018 Feb 26.
The prevalence of metabolic syndrome in youth varies on the basis of the classification system used, prompting implementation of continuous scores; however, the use of these scores is limited to the sample from which they were derived. We sought to describe the derivation of the continuous metabolic syndrome score using nationally representative reference values in a sample of obese adolescents and a national sample obtained from National Health and Nutrition Examination Survey (NHANES) 2011-2012.
Clinical data were collected from 50 adolescents seeking obesity treatment at a stage 3 weight management center. A second analysis relied on data from adolescents included in NHANES 2011-2012, performed for illustrative purposes. The continuous metabolic syndrome score was calculated by regressing individual values onto nationally representative age- and sex-specific standards (NHANES III). Resultant z scores were summed to create a total score.
The final sample included 42 obese adolescents (15 male and 35 female subjects; mean age, 14.8 ± 1.9 years) and an additional 445 participants from NHANES 2011-2012. Among the clinical sample, the mean continuous metabolic syndrome score was 4.16 ± 4.30, while the NHANES sample mean was quite a bit lower, at -0.24 ± 2.8.
We provide a method to calculate the continuous metabolic syndrome by comparing individual risk factor values to age- and sex-specific percentiles from a nationally representative sample.
基于所使用的分类系统，年轻人代谢综合征的患病率有所不同，这促使人们采用连续评分；然而，这些评分的使用仅限于其来源样本。我们试图在肥胖青少年的样本中使用全国代表性参考值来描述连续代谢综合征评分的推导，并在 2011-2012 年全国健康和营养调查（NHANES）中获得全国样本。
从一家 3 级体重管理中心寻求肥胖治疗的 50 名青少年中收集临床数据。第二项分析依赖于 2011-2012 年 NHANES 中包括的青少年的数据，仅用于说明目的。通过将个体值回归到全国代表性的年龄和性别特定标准（NHANES III）来计算连续代谢综合征评分。将产生的 z 分数相加以创建总分。
最终样本包括 42 名肥胖青少年（15 名男性和 35 名女性；平均年龄为 14.8 ± 1.9 岁）和另外 445 名来自 2011-2012 年 NHANES 的参与者。在临床样本中，连续代谢综合征评分的平均值为 4.16 ± 4.30，而 NHANES 样本的平均值低得多，为-0.24 ± 2.8。
我们提供了一种通过将个体风险因素值与全国代表性样本的年龄和性别特定百分位值进行比较来计算连续代谢综合征的方法。
