Motallebnejad Mina, Aminishakib Pouyan, Derakhshan Samira, Karimi Abbas
Department of Oral Medicine, School of Dentistry, Babol University of Medical Sciences, Babol, Iran.
Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Dent Res J (Isfahan). 2018 Jan-Feb;15(1):80-83. doi: 10.4103/1735-3327.223619.
Rhabdomyosarcoma is a malignant skeletal muscle neoplasm. The tumor is much more common in children, and the most frequent site is head and neck region. Since this tumor is less frequent than other neoplasms in oral cavity, the clinicians sometimes ignore it, working the patients up. Rhabdomyosarcoma is a high-grade malignancy with poor prognosis. Considering the aggressive behavior and various clinical or histopathologic presentations of the tumor, early diagnosis has a significant impact on the treatment outcome and prognosis of the patients. We highlight the importance of combining the clinical, radiographic, and histopathologic examination to obtain a definitive diagnosis in sarcomas of the head and neck region, especially rhabdomyosarcoma. A case of rhabdomyosarcoma of the maxillary gingiva is presented in a 32-year-old woman in which the primary incisional biopsy was erroneously interpreted as an inflammatory process and consequently, the accurate diagnosis postponed for about 10 months.
横纹肌肉瘤是一种恶性骨骼肌肿瘤。该肿瘤在儿童中更为常见，最常见的部位是头颈部区域。由于这种肿瘤在口腔中比其他肿瘤少见，临床医生有时会忽视它，从而延误对患者的诊治。横纹肌肉瘤是一种高级别恶性肿瘤，预后较差。考虑到该肿瘤的侵袭性以及各种临床或组织病理学表现，早期诊断对患者的治疗结果和预后具有重大影响。我们强调了结合临床、影像学和组织病理学检查以对头颈部区域肉瘤，尤其是横纹肌肉瘤做出明确诊断的重要性。本文报道了一名32岁女性上颌牙龈横纹肌肉瘤病例，其初次切开活检被错误地诊断为炎症过程，因此准确诊断被推迟了约10个月。
