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儿科功能性腹痛障碍的管理:最新证据。

The Management of Paediatric Functional Abdominal Pain Disorders: Latest Evidence.

机构信息

Pediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, Piazza Menghini 1, 06129, Perugia, Italy.

出版信息

Paediatr Drugs. 2018 Jun;20(3):235-247. doi: 10.1007/s40272-018-0287-z.

Abstract

Recurrent abdominal pain (RAP) is one of the most common health complaints in both children and adults. Although RAP is considered a functional disorder rather than an organic disease, affected children and their families can still experience anxiety and concerns that can interfere with school, sports, and regular daily activities and lead to frequent attendances at pediatric emergency departments or pediatric gastroenterology clinics. Our review shows experts do not agree on a universally proven management that will work on every child presenting with functional abdominal pain (FAP). Treatment strategies include both non-pharmacological and pharmacological options. Non-pharmacological treatments are usually very well accepted by both children and their parents and are free from medication side effects. Nevertheless, they may be as effective as the pharmacological interventions; therefore, according to many experts and based on the majority of current evidence, a non-pharmacological approach should be the first intervention attempt in children with RAP. In particular, the importance of the bio-psychosocial approach is highlighted, as a majority of children will improve with counselling and reassurance that no serious organic pathologies are suspected, especially when the physician establishes a trustful relationship with both the child and their family. Placebo and pharmacological interventions could be attempted when the bio-psychosocial approach is not applicable or not efficacious. In some difficult cases, finding an effective treatment for FAP can be a challenge, and a number of strategies may need to be tried before symptoms are controlled. In these cases, a multidisciplinary team, comprising a pediatric gastroenterologist, dietician, psychologist, and psychotherapist, is likely to be successful.

摘要

复发性腹痛(RAP)是儿童和成人中最常见的健康问题之一。尽管 RAP 被认为是一种功能性障碍而不是器质性疾病,但受影响的儿童及其家庭仍可能会感到焦虑和担忧,这可能会干扰他们的学业、运动和日常活动,并导致频繁前往儿科急诊部门或儿科胃肠病诊所就诊。我们的综述表明,专家们对于针对每个出现功能性腹痛(FAP)的儿童都能有效发挥作用的通用管理方法并未达成一致意见。治疗策略包括非药物和药物治疗。非药物治疗通常非常受儿童及其家长的欢迎,且没有药物的副作用。然而,它们可能与药物干预同样有效;因此,根据许多专家的意见,并基于大多数现有证据,非药物治疗方法应该是 RAP 儿童的首选干预措施。特别是,生物心理社会方法的重要性得到了强调,因为大多数儿童在接受咨询和保证没有可疑的严重器质性病变后会有所改善,尤其是当医生与儿童及其家庭建立了信任关系时。当生物心理社会方法不适用或无效时,可以尝试使用安慰剂和药物干预。在一些棘手的情况下,为 FAP 找到有效的治疗方法可能具有挑战性,可能需要尝试多种策略才能控制症状。在这些情况下,一个多学科团队,包括儿科胃肠病学家、营养师、心理学家和心理治疗师,可能会成功。

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