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经皮椎间孔镜下椎间盘切除术治疗肥胖患者腰椎间盘突出症:2年随访的健康相关生活质量评估

Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc Herniation in Obese Patients: Health-Related Quality of Life Assessment in a 2-Year Follow-Up.

作者信息

Kapetanakis Stylianos, Gkantsinikoudis Nikolaos, Chaniotakis Constantinos, Charitoudis Georgios, Givissis Panagiotis

机构信息

Spine Department and Deformities, Interbalkan European Medical Center, Thessaloniki, Greece.

Spine Department and Deformities, Interbalkan European Medical Center, Thessaloniki, Greece.

出版信息

World Neurosurg. 2018 May;113:e638-e649. doi: 10.1016/j.wneu.2018.02.112. Epub 2018 Feb 28.

DOI:10.1016/j.wneu.2018.02.112
PMID:29499422
Abstract

BACKGROUND

Percutaneous transforaminal endoscopic discectomy (PTED) is a minimally invasive surgical technique used principally for the treatment of lumbar disc herniation (LDH). LDH is a frequent spinal ailment in obese individuals. The aim of this prospectively designed study was to assess for the first time in the literature the impact of PTED in postoperative parameters of health-related quality of life (HRQoL) in obese patients with LDH within a 2-year follow-up period, to further evaluate the effectiveness of PTED.

METHODS

Patients with surgically treatable LDH were divided into 2 groups. Group A constituted 20 obese patients, and group B was composed of 10 patients with normal body mass index (BMI). A visual analog scale was used for pain evaluation, and the Short Form SF-36 Medical Survey Questionnaire contributed to HRQoL assessment. Follow-up was conducted preoperatively and at 6 weeks and 3, 6, 12, and 24 months postoperatively.

RESULTS

Two of the 20 patients (10%) presented with severe postoperative pain, necessitating conventional microdiscectomy. All studied parameters exhibited maximal improvement at 6 months in group A and at 6 weeks in group B, with subsequent stabilization. Obese patients scored lower in all parameters compared with their healthy counterparts with normal BMI, acquiring a less favorable clinical benefit.

CONCLUSIONS

PTED appears to be a generally safe and effective method for treating obese patients with LDH. However, major technical challenges that lead to a higher frequency of complications, as well as the lesser acquired clinical benefit, in obese patients may contribute to the further consideration for PTED in specific obese patients, especially on the grounds of low surgical experience.

摘要

背景

经皮椎间孔镜下椎间盘切除术(PTED)是一种主要用于治疗腰椎间盘突出症(LDH)的微创手术技术。LDH在肥胖个体中是一种常见的脊柱疾病。这项前瞻性设计研究的目的是在文献中首次评估PTED对肥胖LDH患者在2年随访期内与健康相关生活质量(HRQoL)术后参数的影响,以进一步评估PTED的有效性。

方法

将具有手术可治性LDH的患者分为两组。A组由20例肥胖患者组成,B组由10例体重指数(BMI)正常的患者组成。采用视觉模拟量表进行疼痛评估,简短健康调查量表SF - 36用于HRQoL评估。在术前以及术后6周、3、6、12和24个月进行随访。

结果

20例患者中有2例(10%)出现严重术后疼痛,需要进行传统的显微椎间盘切除术。所有研究参数在A组6个月时以及B组6周时表现出最大改善,随后趋于稳定。与BMI正常的健康对照者相比,肥胖患者在所有参数上得分较低,获得的临床益处较差。

结论

PTED似乎是治疗肥胖LDH患者的一种总体安全有效的方法。然而,导致肥胖患者并发症发生率更高以及获得的临床益处较少的主要技术挑战,可能促使在特定肥胖患者中进一步考虑PTED,尤其是基于手术经验不足的情况。

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