Centro Especializado em Plantas Aromáticas, Medicinais e Tóxicas (CEPLAMT), Museu de História Natural e Jardim Botânico, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil; Programa de Pós-Graduação em Medicamentos e Assistência Farmacêutica, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil; Departamento de Assistência Farmacêutica e Insumos Estratégicos, Secretaria de Ciência, Tecnologia e Insumos Estratégicos, Ministério da Saúde, Brasília, DF, Brazil.
Centro Especializado em Plantas Aromáticas, Medicinais e Tóxicas (CEPLAMT), Museu de História Natural e Jardim Botânico, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
J Ethnopharmacol. 2018 Jun 12;219:319-336. doi: 10.1016/j.jep.2018.02.042. Epub 2018 Mar 2.
The World Health Organization (WHO) recognizes the potential of plants used in secular traditional medicine and considers this an important source of evidence to assess their effectiveness and safety. Brazil is rich in biodiversity and traditional uses based on the Amerindian culture. However, many processes started with the arrival of the Portuguese in the year 1500. The successive economic cycles, for example, led to destruction of native vegetation and an intense cultural erosion. As a consequence, the information about the use of plants in the past centuries are dispersed and without interpretation. In this study a methodology to evidence the traditionality of Brazilian plants was demonstrated using data about barbatimão barks (Stryphnodendron adstringens (Mart.) Coville - Fabaceae) and Copaiba oleoresin (Copaifera spp. - Fabaceae) in wound healing, was established.
Data about use of the plants were recovered from bibliography published between 1576 and 2011. The books (101) were classified using weights, considering the date of publication and the source of Information. Older books that describe primary information received weight 10, while books written more recently and with secondary information received weight 0.4. A score for each category of medicinal use was calculated based on the books weights and the frequency of citation. A review about the current use of both plants was also performed from ethnobotanical studies published in journals.
The traditional secular use of barks of barbatimão and oleoresin of copaiba to treat wounds was confirmed based on the historic bibliographic research. The most frequent use of barbatimão in a timeline of 500 years of Brazil's history, was as astringent, whereas for copaíba was as healing of skin and mucosal lesions. The continuous and current use of these plants to treat wounds, confirmed by recent ethnobotanical studies, is an indicative of the resilience of these remedies and their effectiveness.
The use of preparations containing barbatimão barks and copaiba oleoresin can be considered effective in the treatment of wounds. Nonetheless, it is necessary to improve the quality of the formulas as established by WHO.
世界卫生组织（WHO）认识到常用于世俗传统医学的植物的潜力，并认为这是评估其有效性和安全性的重要证据来源。巴西拥有丰富的生物多样性和基于美洲原住民文化的传统用途。然而，许多过程始于 1500 年葡萄牙人的到来。例如，连续的经济周期导致了原生植被的破坏和强烈的文化侵蚀。因此，关于过去几个世纪植物使用情况的信息分散且没有解释。在这项研究中，展示了一种使用有关巴巴图树树皮（Stryphnodendron adstringens (Mart.) Coville-豆科）和库巴香油（Copaifera spp.-豆科）在伤口愈合方面的传统用途的巴西植物的数据的方法。
从 1576 年至 2011 年期间发表的文献中检索有关植物使用的数据。使用权重对书籍进行分类，考虑出版日期和信息来源。描述原始信息的较旧书籍获得权重 10，而最近编写且具有次要信息的书籍获得权重 0.4。根据书籍权重和引用频率计算每个药用类别得分。还从发表在期刊上的民族植物学研究中对这两种植物的当前用途进行了综述。
根据历史文献研究，确认了巴巴图树树皮和库巴香油用于治疗伤口的世俗传统用途。在巴西 500 年历史的时间轴上，巴巴图树最常见的用途是收敛剂，而库巴油则是治疗皮肤和粘膜损伤。最近的民族植物学研究证实，这些植物持续且当前用于治疗伤口，这表明这些疗法具有弹性且有效。
使用含有巴巴图树树皮和库巴香油的制剂可被认为对伤口治疗有效。尽管如此，仍有必要按照世界卫生组织的规定提高配方质量。
