Sifuna Peter, Otieno Lucas, Ogwang Sheila, Ogutu Bernhards, Andagalu Ben, Owuoth John, Singoei Valentine, Cowden Jessica, Otieno Walter
a US Army Medical Research Directorate-Kenya (USAMRD-K)/Kenya Medical Research Institute (KEMRI) , Kisumu , Kenya.
b INDEPTH Network , Accra , Ghana.
Glob Health Action. 2018;11(1):1442959. doi: 10.1080/16549716.2018.1442959.
The vast majority of deaths in the health and Kombewa demographic surveillance system (HDSS) study area are not registered and reported through official systems of vital registration. As a result, few data are available regarding causes of death in this population.
To describe causes of death among residents of all ages in the Kombewa HDSS, located in rural Western Kenya.
Verbal autopsy (VA) interviews at the site were conducted using the modified 2007 and later 2012 standardized WHO questionnaires. Assignment of causes of death was made using the InterVA-4 model version 4.02. Cox regression model, adjusted for sex, was built to evaluate the influence of age on mortality.
There were a total of 5196 deaths recorded between 2011 and 2015 at the site. VA interviews were successfully completed for 3903 of these deaths (75.1%). Mortality rates were highest among neonates HR = 38.54 (<0.001) and among Infants HR = 2.07 (<0.006) in the Kombewa HDSS. Among those deaths in which VA was performed, the top causes of death were HIV/AIDS (12.6%), Malaria (10.3%), Pneumonia (10.1%), Acute abdomen (7.0%), Stroke (5.2%) and TB (4.9%) for the whole population in general. Stroke, acute abdomen heart diseases and Pneumonia were common causes of death (CODs) among the elderly over the age of 65.
The analysis established the main CODs among people of all ages within the area served by the Kombewa HDSS. We hope that information generated from this study will help better address preventable deaths in the surveyed community as well as help mitigate negative health impacts in other rural communities throughout the Western Kenya region.
在健康与孔贝瓦人口监测系统（HDSS）研究区域，绝大多数死亡并未通过官方生命登记系统进行登记和报告。因此，关于该人群死因的数据很少。
描述位于肯尼亚西部农村的孔贝瓦HDSS中各年龄段居民的死因。
在该地点进行口头尸检（VA）访谈时，使用了经修改的2007年及之后2012年的世卫组织标准化问卷。死因判定采用InterVA - 4模型4.02版本。构建了经性别调整的Cox回归模型，以评估年龄对死亡率的影响。
2011年至2015年期间，该地点共记录了5196例死亡。其中3,903例死亡成功完成了VA访谈（75.1%）。在孔贝瓦HDSS中，新生儿死亡率最高（HR = 38.54，<0.001），婴儿死亡率次之（HR = 2.07，<0.006）。在进行了VA的死亡病例中，总体全人群的主要死因依次为艾滋病毒/艾滋病（12.6%）、疟疾（10.3%）、肺炎（10.1%）、急腹症（7.0%）、中风（5.2%）和结核病（4.9%）。中风、急腹症、心脏病和肺炎是65岁以上老年人常见的死因。
该分析确定了孔贝瓦HDSS所服务区域内各年龄段人群的主要死因。我们希望本研究产生的信息将有助于更好地解决被调查社区中可预防的死亡问题，并有助于减轻肯尼亚西部其他农村社区的负面健康影响。
