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肯尼亚基苏木县疟疾流行地区成年人疟原虫感染率及其影响因素

Prevalence of malaria parasites in adults and its determinants in malaria endemic area of Kisumu County, Kenya.

作者信息

Jenkins Rachel, Omollo Raymond, Ongecha Michael, Sifuna Peter, Othieno Caleb, Ongeri Linnet, Kingora James, Ogutu Bernhards

机构信息

Health Services Research Department, Institute of Psychiatry, Kings College London, de Crespigny Park, London, SE5 8AF, UK.

Kenya Medical Research Institute, Nairobi, Kenya.

出版信息

Malar J. 2015 Jul 8;14:263. doi: 10.1186/s12936-015-0781-5.

Abstract

BACKGROUND

The prevalence of malaria parasites in adults in Africa is less well researched than in children. Therefore, a demographic surveillance site was used to conduct a household survey of adults in the malaria endemic area of Maseno division in Kisumu County near Lake Victoria.

METHODS

A random survey of 1,190 adults living in a demographic health surveillance site in a malaria endemic area of 70,805 population size was conducted, measuring presence of malaria parasites by slide microscopy. Data were analysed using STATA to calculate the prevalence of malaria and associated risk factors.

RESULTS

The adult prevalence of presence of malaria parasites in Maseno was 28% (95% CI: 25.4-31.0%). Gender was a significant sociodemographic risk factor in both univariate (OR 1.5, p = 0.005) and multivariate (OR 1.4, p = 0.019) analyses. Females were 50% more likely to have malaria than men.

CONCLUSIONS

Presence of malaria parasites is common in the adult population of this endemic area, and the rate is greatly increased in women. The presence of such an adult pool of malaria parasites represents a key reservoir factor in transmission of parasites to children, and is relevant for plans to eradicate malaria.

摘要

背景

与儿童相比,非洲成年人中疟原虫的流行情况研究较少。因此,利用一个人口监测点对维多利亚湖附近基苏木县马塞诺分区疟疾流行地区的成年人进行了一项家庭调查。

方法

对生活在一个人口为70805的疟疾流行地区的人口健康监测点的1190名成年人进行了随机调查,通过玻片显微镜检查测量疟原虫的存在情况。使用STATA软件分析数据,以计算疟疾的流行率和相关危险因素。

结果

马塞诺成年人中疟原虫的流行率为28%(95%可信区间:25.4-31.0%)。在单因素分析(比值比1.5,p = 0.005)和多因素分析(比值比1.4,p = 0.019)中,性别都是一个显著的社会人口学危险因素。女性感染疟疾的可能性比男性高50%。

结论

在这个流行地区的成年人群中,疟原虫的存在很常见,而且女性的感染率大大增加。如此大量成年疟原虫感染者的存在是寄生虫传播给儿童的一个关键储存因素,与疟疾根除计划相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2668/4495611/1ea4172b5970/12936_2015_781_Fig1_HTML.jpg

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