Mmopelwa Tiro, Ayhan Selim, Yuksel Selcen, Nabiyev Vugar, Niyazi Asli, Pellise Ferran, Alanay Ahmet, Sanchez Perez Grueso Francisco Javier, Kleinstuck Frank, Obeid Ibrahim, Acaroglu Emre
ARTES Spine Center, Ankara, Turkey.
ARTES Spine Center, Ankara, Turkey; Acibadem University Vocational School of Health Sciences, Istanbul, Turkey.
Acta Orthop Traumatol Turc. 2018 May;52(3):179-184. doi: 10.1016/j.aott.2018.02.001. Epub 2018 Mar 2.
To identify the factors that affect SF-36 mental component summary (MCS) in patients with adult spinal deformity (ASD) at the time of presentation, and to analyse the effect of SF-36 MCS on clinical outcomes in surgically treated patients.
Prospectively collected data from a multicentric ASD database was analysed for baseline parameters. Then, the same database for surgically treated patients with a minimum of 1-year follow-up was analysed to see the effect of baseline SF-36 MCS on treatment results. A clinically useful SF-36 MCS was determined by ROC Curve analysis.
A total of 229 patients with the baseline parameters were analysed. A strong correlation between SF-36 MCS and SRS-22, ODI, gender, and diagnosis were found (p < 0.05). For the second part of the study, a total of 186 surgically treated patients were analysed. Only for SF-36 PCS, the un-improved cohort based on minimum clinically important differences had significantly lower mean baseline SF-36 MCS (p < 0.001). SF-36 MCS was found to have an odds ratio of 0.914 in improving SF-36 PCS score (unit by unit) (p < 0.001). A cut-off point of 43.97 for SF-36 MCS was found to be predictive of SF-36 PCS (AUC = 0.631; p < 0.001).
The factors effective on the baseline SF-36 MCS in an ASD population are other HRQOL parameters such as SRS-22 and ODI as well as the baseline thoracic kyphosis and gender. This study has also demonstrated that baseline SF-36 MCS does not necessarily have any effect on the treatment results by surgery as assessed by SRS-22 or ODI.
Level III, prognostic study.
确定成年脊柱畸形（ASD）患者就诊时影响SF-36精神健康综合评分（MCS）的因素，并分析SF-36 MCS对手术治疗患者临床结局的影响。
对前瞻性收集的多中心ASD数据库中的基线参数进行分析。然后，对同一数据库中至少随访1年的手术治疗患者进行分析，以观察基线SF-36 MCS对治疗结果的影响。通过ROC曲线分析确定具有临床意义的SF-36 MCS。
共分析了229例具有基线参数的患者。发现SF-36 MCS与SRS-22、ODI、性别和诊断之间存在强相关性（p<0.05）。在研究的第二部分，共分析了186例手术治疗患者。仅对于SF-36生理健康综合评分（PCS），基于最小临床重要差异未改善的队列其平均基线SF-36 MCS显著更低（p<0.001）。发现SF-36 MCS在改善SF-36 PCS评分方面（单位评分）的优势比为0.914（p<0.001）。发现SF-36 MCS的截断值为43.97时可预测SF-36 PCS（曲线下面积=0.631；p<0.001）。
在ASD人群中，对基线SF-36 MCS有影响的因素包括其他健康相关生活质量参数，如SRS-22和ODI，以及基线胸椎后凸和性别。本研究还表明，基线SF-36 MCS不一定对手术治疗结果有任何影响，这一结果通过SRS-22或ODI评估得出。
III级，预后研究。
