Müller A
Horm Metab Res Suppl. 1979(8):33-5.
Common polarimeters defined the concentration of an optically active sample by measuring the intensity of the light beam after it has passed through the analyser. Consequently, it can be stated that up to now, there have been the disadvantages of having a signal dependent on absolute light intensity. The new method that is described has a sensitivity that is in great measure independent of absolute light intensity, whereby only one light trace is necessary. The new principle uses no mechanical rotations. Instead, an electrical signal indicates the amount of optical rotation of the sample. The high sensitivity that can be reached is theoretically only limited by polarization noise. By going to the uttermost physical and electronic lengths, sensitivity values of more than 10(-5) degrees can be reached. Furthermore, the mechanical dimensions of the apparatus can be made very small by the application of a solid-state laser.
普通旋光仪通过测量光束透过检偏器后的强度来确定旋光性样品的浓度。因此，可以说直到现在，一直存在信号依赖于绝对光强的缺点。所描述的新方法具有在很大程度上独立于绝对光强的灵敏度，从而只需要一条光迹。新原理不使用机械旋转。相反，一个电信号指示样品的旋光度。理论上所能达到的高灵敏度仅受偏振噪声限制。通过在物理和电子方面做到极致，可以达到超过10^(-5)度的灵敏度值。此外，通过应用固态激光器，该仪器的机械尺寸可以做得非常小。
