Wang Jay C, Burkholder Bryn M, Butler Nicholas J
Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.
Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins School of Medicine, 2 Nelson, 600 N Wolfe Street, Baltimore, MD 21287, USA.
Am J Ophthalmol Case Rep. 2016 Apr 29;3:22-24. doi: 10.1016/j.ajoc.2016.04.009. eCollection 2016 Oct.
To report a case of retinal vasculitis associated with birdshot chorioretinitis which was responsive to topical difluprednate alone.
Two months after initiation of topical difluprednate, fluorescein angiography demonstrated resolution of retinal vasculitis in both treated eyes. Worsening of vasculitis with attempted taper of difluprednate and subsequent control with prior dosing confirmed the response.
Despite potential adverse effects of steroid-induced glaucoma and cataract formation, topical difluprednate in the treatment of retinal vasculitis and other posterior uveitides may have efficacy.
报告一例与鸟枪弹样视网膜脉络膜炎相关的视网膜血管炎病例，该病例仅局部使用二氟泼尼酯即可有效。
开始局部使用二氟泼尼酯两个月后，荧光素血管造影显示两只治疗眼的视网膜血管炎均消退。在尝试逐渐减少二氟泼尼酯用量时血管炎加重，随后恢复之前的用药剂量后得到控制，这证实了药物的疗效。
尽管存在类固醇诱导的青光眼和白内障形成等潜在不良反应，但局部使用二氟泼尼酯治疗视网膜血管炎和其他后葡萄膜炎可能有效。
