每日两次局部应用地夫可特 0.05%乳剂治疗渗出性视网膜炎的疗效。
Effects of twice-daily topical difluprednate 0.05% emulsion in a child with pars planitis.
机构信息
Ohio State University, Havener Eye Institute, 915 Olentangy River Road, Columbus, OH 43212, USA.
出版信息
Ocul Immunol Inflamm. 2011 Feb;19(1):84-5. doi: 10.3109/09273948.2010.512993. Epub 2010 Oct 31.
PURPOSE
To report the effects of twice-daily difluprednate in a child with pars planitis (PP).
DESIGN/METHODS: Case report.
RESULTS
PP was controlled with topical difluprednate for 1 year. Then an atypical pattern of steroid response--delayed, relatively sudden onset of recalcitrant ocular hypertension (OHT)--and posterior subcapsular cataract (PSC) formation necessitated alternative treatment.
CONCLUSION
Although not a standard treatment, in select cases of PP topical difluprednate therapy could be a useful short-term treatment option while alternative treatments are considered or immunosuppressive agents build to therapeutic levels. Ophthalmologists must be aware of the potential for delayed onset of serious complications when using difluprednate.
目的
报告每日两次使用双氯苯噁唑酸治疗睫状体平坦部炎（PP）儿童的效果。
方法/设计：病例报告。
结果
局部使用双氯苯噁唑酸治疗 1 年后，PP 得到控制。随后出现了一种非典型的类固醇反应模式——延迟、相对突然出现的难治性眼高压（OHT）和后囊下白内障（PSC）形成，需要替代治疗。
结论
尽管不是标准治疗方法，但在选择的 PP 病例中，局部使用双氯苯噁唑酸治疗可能是一种有用的短期治疗选择，同时可以考虑其他治疗方法或免疫抑制剂达到治疗水平。眼科医生在使用双氯苯噁唑酸时必须意识到严重并发症延迟发生的可能性。
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