艰难梭菌感染的实验室诊断陷阱 - Suppr

The pitfalls of laboratory diagnostics of Clostridium difficile infection.

作者信息

Krutova M, Wilcox M H, Kuijper E J

机构信息

Department of Medical Microbiology, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic; European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Clostridium difficile (ESGCD).

Leeds Teaching Hospitals NHS Trust & University of Leeds, Leeds, United Kingdom; European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Clostridium difficile (ESGCD).

出版信息

Clin Microbiol Infect. 2018 Jul;24(7):682-683. doi: 10.1016/j.cmi.2018.02.026. Epub 2018 Mar 2.

DOI:10.1016/j.cmi.2018.02.026

PMID:29505883

Abstract

摘要

相似文献

The pitfalls of laboratory diagnostics of Clostridium difficile infection.艰难梭菌感染的实验室诊断陷阱

Clin Microbiol Infect. 2018 Jul;24(7):682-683. doi: 10.1016/j.cmi.2018.02.026. Epub 2018 Mar 2.

Diagnostic trends in Clostridium difficile detection in Finnish microbiology laboratories.芬兰微生物学实验室中艰难梭菌检测的诊断趋势。

Anaerobe. 2009 Dec;15(6):261-5. doi: 10.1016/j.anaerobe.2009.06.008. Epub 2009 Jul 8.

Detection of Clostridium difficile toxin genes by PCR: sequence variation may cause false-negative results.通过聚合酶链反应检测艰难梭菌毒素基因：序列变异可能导致假阴性结果。

J Med Microbiol. 2015 Feb;64(Pt 2):195-197. doi: 10.1099/jmm.0.081364-0. Epub 2014 Dec 5.

Two-step algorithm for the detection of Clostridium difficile from stool samples.用于从粪便样本中检测艰难梭菌的两步算法。

J Hosp Infect. 2011 Sep;79(1):95-6; author reply 96-7. doi: 10.1016/j.jhin.2011.04.002. Epub 2011 Jun 2.

Epidemiological survey of Clostridium difficile ribotypes in the North East of England during an 18-month period.英格兰东北部在 18 个月期间艰难梭菌核糖体分型的流行病学调查。

J Hosp Infect. 2012 Jul;81(3):209-12. doi: 10.1016/j.jhin.2012.04.017. Epub 2012 May 24.

Rapid detection of Clostridium difficile toxins and laboratory diagnosis of Clostridium difficile infections.艰难梭菌毒素的快速检测及艰难梭菌感染的实验室诊断

Infection. 2017 Jun;45(3):255-262. doi: 10.1007/s15010-016-0940-9. Epub 2016 Sep 6.

Spread and persistence of Clostridium difficile spores during and after cleaning with sporicidal disinfectants.艰难梭菌孢子在用杀孢子消毒剂清洁期间及之后的传播与持续存在情况。

J Hosp Infect. 2011 Sep;79(1):97-8. doi: 10.1016/j.jhin.2011.06.010. Epub 2011 Jul 19.

Re: Spread and persistence of Clostridium difficile spores during and after cleaning with sporicidal disinfectants.关于：艰难梭菌孢子在用杀孢子消毒剂清洁期间及之后的传播与持续存在情况。

J Hosp Infect. 2012 Feb;80(2):185; author reply 186. doi: 10.1016/j.jhin.2011.10.016. Epub 2011 Dec 14.

Clonal spread of a Clostridium difficile strain with a complete set of toxin A, toxin B, and binary toxin genes among Polish patients with Clostridium difficile-associated diarrhea.一株携带完整毒素A、毒素B和二元毒素基因的艰难梭菌在波兰艰难梭菌相关性腹泻患者中的克隆传播。

J Clin Microbiol. 2005 Jan;43(1):472-5. doi: 10.1128/JCM.43.1.472-475.2005.

Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A and B testing on stool samples.尽管粪便样本毒素 A 和 B 检测呈阴性，但仍能检测出医院获得性艰难梭菌感染的产毒株。

Clin Microbiol Infect. 2014 Sep;20(9):O590-2. doi: 10.1111/1469-0691.12558. Epub 2014 Feb 20.

引用本文的文献

Genomic islands and molecular mechanisms relating to drug-resistance in () PCR ribotype 176.与PCR核糖体分型176相关的基因组岛及耐药性分子机制。（括号内容原文缺失）

Emerg Microbes Infect. 2025 Dec;14(1):2482698. doi: 10.1080/22221751.2025.2482698. Epub 2025 Apr 9.

Clostridioides difficile Infection: A Clinical Review of Pathogenesis, Clinical Considerations, and Treatment Strategies.艰难梭菌感染：发病机制、临床考量及治疗策略的临床综述

Cureus. 2023 Dec 27;15(12):e51167. doi: 10.7759/cureus.51167. eCollection 2023 Dec.

Diagnostic Methods of Infection and Ribotypes in Studied Sample.所研究样本中感染及核糖型的诊断方法

Antibiotics (Basel). 2021 Aug 25;10(9):1035. doi: 10.3390/antibiotics10091035.

Clinical impact of a () bedside infectious disease stewardship intervention.一种（）床边传染病管理干预措施的临床影响。（注：原文括号处内容缺失）

JAC Antimicrob Resist. 2020 Aug 11;2(3):dlaa037. doi: 10.1093/jacamr/dlaa037. eCollection 2020 Sep.

The Colonisation of Calves in Czech Large-Scale Dairy Farms by Clonally-Related of the Sequence Type 11 Represented by Ribotypes 033 and 126.捷克大型奶牛场中由核糖体分型033和126所代表的序列型11的克隆相关菌株对犊牛的定植情况

Microorganisms. 2020 Jun 15;8(6):901. doi: 10.3390/microorganisms8060901.

Physical, Laboratory, Radiographic, and Endoscopic Workup for Colitis.结肠炎的体格检查、实验室检查、影像学检查及内镜检查

Clin Colon Rectal Surg. 2020 Mar;33(2):82-86. doi: 10.1055/s-0039-3400474. Epub 2020 Feb 25.

The emergence of Clostridium difficile ribotypes 027 and 176 with a predominance of the Clostridium difficile ribotype 001 recognized in Slovakia following the European standardized Clostridium difficile infection surveillance of 2016.继 2016 年欧洲标准化艰难梭菌感染监测之后，在斯洛伐克发现了以优势流行的艰难梭菌 027 和 176 型为主的艰难梭菌 001 型。

Int J Infect Dis. 2020 Jan;90:111-115. doi: 10.1016/j.ijid.2019.10.038. Epub 2019 Nov 9.

Evaluation of a Gastrointestinal Pathogen Panel Immunoassay in Stool Testing of Patients with Suspected () Infection.粪便检测疑似 () 感染患者的胃肠道病原体面板免疫测定评估。

J Clin Microbiol. 2019 Sep 24;57(10). doi: 10.1128/JCM.00710-19. Print 2019 Oct.

First genotypic characterization of toxigenic Clostridioides difficile in Lithuanian hospitals reveals the prevalence of the hypervirulent ribotype 027/ST1.首次对立陶宛医院产毒艰难梭菌的基因分型特征进行了研究，结果显示了高毒力核糖体型 027/ST1 的流行。

Eur J Clin Microbiol Infect Dis. 2019 Oct;38(10):1953-1959. doi: 10.1007/s10096-019-03633-9. Epub 2019 Jul 20.

Quantification of Clostridioides (Clostridium) difficile in feces of calves of different age and determination of predominant Clostridioides difficile ribotype 033 relatedness and transmission between family dairy farms using multilocus variable-number tandem-repeat analysis.不同年龄犊牛粪便中艰难梭菌的定量分析，以及使用多位点可变数目串联重复序列分析确定主要的艰难梭菌核糖体分型033在家庭奶牛场之间的相关性和传播情况。

BMC Vet Res. 2018 Oct 1;14(1):298. doi: 10.1186/s12917-018-1616-8.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The pitfalls of laboratory diagnostics of Clostridium difficile infection.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献