一株携带完整毒素A、毒素B和二元毒素基因的艰难梭菌在波兰艰难梭菌相关性腹泻患者中的克隆传播。
Clonal spread of a Clostridium difficile strain with a complete set of toxin A, toxin B, and binary toxin genes among Polish patients with Clostridium difficile-associated diarrhea.
作者信息
Pituch Hanna, Kreft Deborah, Obuch-Woszczatynski Piotr, Wultańska Dorota, Meisel-Mikołajczyk Felicja, Łuczak Mirosław, van Belkum Alex
机构信息
Department of Medical Microbiology, The Medical University of Warsaw, 5 Chalubinski Street, 02-004 Warsaw, Poland.
出版信息
J Clin Microbiol. 2005 Jan;43(1):472-5. doi: 10.1128/JCM.43.1.472-475.2005.
Abstract
Clinically relevant Clostridium difficile strains usually produce toxins A and B. Some C. difficile strains can produce an additional binary toxin. We report clonality among five strains carrying all toxin genes from Polish patients with C. difficile-associated diarrhea. In another strain, possible recombination between binary toxin genes is documented.
摘要
具有临床相关性的艰难梭菌菌株通常会产生毒素A和毒素B。一些艰难梭菌菌株还可产生一种额外的二元毒素。我们报告了来自波兰艰难梭菌相关性腹泻患者的五株携带所有毒素基因的菌株之间的克隆性。在另一株菌株中，记录到二元毒素基因之间可能发生了重组。
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