a Endemic Medicine Department, Faculty of Medicine , Helwan University , Cairo , Egypt.
b Endemic Hepatogastroenterology, Faculty of Medicine , Cairo University , Cairo , Egypt.
Expert Rev Anti Infect Ther. 2018 Apr;16(4):345-350. doi: 10.1080/14787210.2018.1448709. Epub 2018 Mar 11.
Currently, direct-acting antivirals (DAAs) are considered the ideal choice for the treatment of chronic HCV patients due to their proven efficacy (SVR> 90%), and minimal adverse effects. Egypt launched a large treatment program aimed at providing treatment coverage for Egyptian HCV- infected patients. Areas covered: This review covers the treatment and prevention efforts made by the Egyptian National Committee for the Control of Viral Hepatitis (NCCVH) with the available model of care for HCV patients in Egypt, in addition to the barriers that prevent elimination of HCV from Egypt. Expert commentary: Egypt could provide a model for establishing the largest HCV management system aimed at eliminating HCV from the country with the highest worldwide prevalence. Despite the huge efforts and achieved results in combating the HCV epidemic in Egypt, certain improvements are needed in order to attain HCV elimination, such as the development of an enhanced screening program working in parallel to the present treatment options.
目前，直接作用抗病毒药物（DAAs）因其已被证实的疗效（SVR>90%）和最小的不良反应而被认为是治疗慢性 HCV 患者的理想选择。埃及启动了一项大规模的治疗计划，旨在为埃及 HCV 感染患者提供治疗覆盖。涵盖领域：本综述涵盖了埃及国家病毒性肝炎控制委员会（NCCVH）为埃及 HCV 患者提供现有护理模式所做的治疗和预防工作，以及阻止埃及消除 HCV 的障碍。专家评论：埃及可以为建立全球 HCV 管理系统树立一个典范，旨在通过全球 HCV 发病率最高的国家消除 HCV。尽管埃及在防治 HCV 流行方面做出了巨大努力并取得了成果，但仍需要在某些方面加以改进，以实现 HCV 的消除，例如开发一个增强的筛查计划，与现有的治疗方案并行开展。
