Andersen Lasse Østergaard, Enggaard Thomas Peter, Højsted Jette
Ugeskr Laeger. 2018 Feb 26;180(9).
Pharmacological treatment of neuropathic pain is associated with side effects and limited efficacy. Recently, the interest in cannabis-based medicine has led to legalisation of medical cannabis in some countries. The aim of this review is to evaluate the evidence of cannabinoids in neuropathic pain. Seventeen trials were identified; eight reported an analgesic efficacy of cannabis-based medicine, and the remaining trials showed no analgesic efficacy. Conclusions were limited by design of studies and short duration of treatment. Overall, the reduction in pain was minimal.
神经性疼痛的药物治疗存在副作用且疗效有限。最近，对大麻类药物的关注促使一些国家将医用大麻合法化。本综述的目的是评估大麻素治疗神经性疼痛的证据。共确定了17项试验；其中8项报告了大麻类药物的镇痛效果，其余试验未显示出镇痛效果。研究结论受到研究设计和治疗时间短的限制。总体而言，疼痛减轻程度极小。
