Poon M K L, Wong J P H, Li A T W, Manuba M, Bisignano A, Owino M, Vahabi M
School of Social Work, York University, Toronto, ON.
Daphne Cockwell School of Nursing, Ryerson University, Toronto, ON.
Curr Oncol. 2018 Feb;25(1):e83-e89. doi: 10.3747/co.25.3856. Epub 2018 Feb 28.
Human papillomavirus (hpv) infection is the cause of anal squamous cell cancer (ascc) in 80% of cases. Available research has also shown high prevalence of anal hpv infection among men who have sex with men (msm). However, hpv vaccination is low among msm in Canada. In light of this information, we conducted a scoping review with the aim of exploring (1) the knowledge of hpv and anal cancer among hiv-positive msm and (2) the acceptability of hpv and anal cancer self-sampling in this population. In conducting the review, we searched five electronic databases for peer-reviewed articles and abstracts published in English, between 2007 and 2017. A total of 803 articles were retrieved; after accounting for duplicates (40) and unmet criteria (754), a total of 794 articles were excluded. A final total of nine articles were used in this review. Results of this review show that hiv-positive msm have limited knowledge regarding the risks of anal cancer associated with hiv and hpv coinfection. Furthermore, there is limited research on hpv and anal cancer self-sampling in this population. However, the review of available studies suggested that hiv-positive msm were open to anal cancer self-sampling. It also identified potential barriers to self-sampling. In conclusion, we provide suggestions and future directions for policy-makers and educators to develop inclusive and accessible strategies to reach hiv-positive msm regarding anal cancer education and self-screening.
人乳头瘤病毒（HPV）感染是80%的肛门鳞状细胞癌（ASCC）病例的病因。现有研究还表明，男男性行为者（MSM）中肛门HPV感染的患病率很高。然而，加拿大男男性行为者中HPV疫苗接种率较低。鉴于这一信息，我们进行了一项范围综述，旨在探讨（1）HIV阳性男男性行为者对HPV和肛门癌的了解情况，以及（2）该人群对HPV和肛门癌自我采样的接受程度。在进行综述时，我们在五个电子数据库中搜索了2007年至2017年期间以英文发表的同行评审文章和摘要。共检索到803篇文章；在剔除重复文章（40篇）和不符合标准的文章（754篇）后，总共排除了794篇文章。本综述最终共使用了9篇文章。该综述结果表明，HIV阳性男男性行为者对与HIV和HPV合并感染相关的肛门癌风险了解有限。此外，针对该人群中HPV和肛门癌自我采样的研究也很有限。然而，对现有研究的综述表明，HIV阳性男男性行为者对肛门癌自我采样持开放态度。研究还确定了自我采样的潜在障碍。总之，我们为政策制定者和教育工作者提供了建议和未来方向，以制定包容性和可及性的策略，向HIV阳性男男性行为者开展肛门癌教育和自我筛查。
