Ng'ang'a Pauline W, Mathai Muthoni, Obondo Anne, Mutavi Teresia, Kumar Manasi
1Department of Psychiatry, College of Health Sciences, University of Nairobi, P O Box 19676, Nairobi, 00202 Kenya.
2Research Department of Clinical Health and Educational Psychology, University College London, London, WC1E 7HB UK.
Ann Gen Psychiatry. 2018 Mar 2;17:11. doi: 10.1186/s12991-018-0179-1. eCollection 2018.
Psychiatric morbidity is commonly associated with HIV disease and may have adverse effects. This aspect may be overlooked at comprehensive HIV care centers in Low and Middle-Income Countries.
The aim of this study was to determine the prevalence of undetected psychiatric morbidity among HIV/AIDS adult patients attending Comprehensive Care Centre in a semi-urban clinic, in Nairobi, Kenya.
Descriptive cross-sectional study of adult HIV patients not receiving any psychiatric treatment was conducted.
PARTICIPANTS/METHODS: The participants consisted of consecutive sample of adults ( = 245) attending HIV Comprehensive Care Clinic at Kangemi Health Centre, Nairobi. The Mini International Neuropsychiatric Interview (MINI) was administered to screen for undetected psychiatric morbidity. Socio-demographic characteristics were recorded in a questionnaire. Sample descriptive analysis was performed and prevalence of undetected psychiatric morbidity calculated. Chi-square test for independence was used to examine the associations between patient characteristics and undetected morbidity. Multivariable logistic regression analysis was performed to determine independent predictors of undetected psychiatric morbidity.
The mean age of our participants was 37.3 years (SD 9.2) Three-quarters (75.9%) of participants were females and median duration of HIV illness was 5 years. The prevalence of (previously undetected) psychiatric morbidity was 71.4% (95% CI 65.3-77). The leading psychiatric disorders were MDD (32.2%), PTSD (18.4%), Dysthymia (17.6%), and OCD (17.6%). Overall psychiatric morbidity was associated with low income (<USD 30), = 0.035. MDD was associated with older age and female gender. There were no statistically significant associations between overall psychiatric morbidity and social determinants such as gender, marital status, level of education, religious affiliation, and occupation or employment status.
The burden of psychiatric morbidity in Kenyan HIV patients remains high and is most significantly associated with lower socioeconomic status. There is need to provide holistic care including screening for mental well-being all through the treatment of HIV patients in low-income settings.
精神疾病常与艾滋病毒疾病相关联,且可能产生不利影响。在低收入和中等收入国家的综合艾滋病毒护理中心,这一方面可能被忽视。
本研究的目的是确定在肯尼亚内罗毕一个半城市诊所的综合护理中心就诊的艾滋病毒/艾滋病成年患者中未被发现的精神疾病患病率。
对未接受任何精神治疗的成年艾滋病毒患者进行描述性横断面研究。
参与者/方法:参与者包括在内罗毕坎杰米健康中心艾滋病毒综合护理诊所就诊的连续样本成年人(n = 245)。采用迷你国际神经精神访谈(MINI)进行筛查,以发现未被诊断的精神疾病。通过问卷记录社会人口学特征。进行样本描述性分析并计算未被发现的精神疾病患病率。使用卡方独立性检验来检查患者特征与未被发现的疾病之间的关联。进行多变量逻辑回归分析以确定未被发现的精神疾病的独立预测因素。
参与者的平均年龄为37.3岁(标准差9.2)。四分之三(75.9%)的参与者为女性,艾滋病毒疾病的中位病程为5年。(先前未被发现的)精神疾病患病率为71.4%(95%置信区间65.3 - 77)。主要的精神障碍是重度抑郁症(32.2%)、创伤后应激障碍(18.4%)、心境恶劣障碍(17.6%)和强迫症(17.6%)。总体精神疾病与低收入(<30美元)相关,P = 0.035。重度抑郁症与年龄较大和女性性别相关。总体精神疾病与性别、婚姻状况、教育水平、宗教信仰以及职业或就业状况等社会决定因素之间无统计学显著关联。
肯尼亚艾滋病毒患者的精神疾病负担仍然很高,且与较低的社会经济地位最为显著相关。在低收入环境中,有必要在艾滋病毒患者的整个治疗过程中提供全面护理,包括对心理健康进行筛查。