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“啤酒性低钠血症”——一种具有独特病理生理学的严重低钠血症综合征:病例研究与文献综述

"Beer Potomania" - A Syndrome of Severe Hyponatremia with Unique Pathophysiology: Case Studies and Literature Review.

作者信息

Lodhi Muhammad Uzair, Saleem Tahira Sabeen, Kuzel Aaron R, Khan Dawood, Syed Intekhab Askari, Rahim Umar, Iqbal Hafiz Imran, Rahim Mustafa

机构信息

Medical Student, Department of Medicine, Raleigh General Hospital, Beckley, Wv.

Department of Medicine, Raleigh General Hospital, Beckley, Wv.

出版信息

Cureus. 2017 Dec 29;9(12):e2000. doi: 10.7759/cureus.2000.

Abstract

Beer potomania, a unique syndrome of hyponatremia, was first reported in 1972. It is described as the excessive intake of alcohol, particularly beer, together with poor dietary solute intake that leads to fatigue, dizziness, and muscular weakness. The low solute content of beer, and suppressive effect of alcohol on proteolysis result in reduced solute delivery to the kidney. The presence of inadequate solute in the kidney eventually causes dilutional hyponatremia secondary to reduced clearance of excess fluid from the body. Early detection of hyponatremia due to beer potomania in the hospital is necessary to carefully manage the patient in order to avoid neurological consequences as this syndrome has unique pathophysiology. We are reporting two cases, presenting to the emergency department with severe hyponatremia. After a detailed initial evaluation of the patients and labs for hyponatremia, a diagnosis of beer potomania was established in both cases. Considering the unique pathophysiology of beer potomania syndrome, the patients were closely monitored and treated appropriately to prevent any neurological sequelae.

摘要

啤酒狂饮性低钠血症是一种独特的低钠血症综合征,于1972年首次被报道。它被描述为过量摄入酒精,尤其是啤酒,同时饮食中溶质摄入不足,导致疲劳、头晕和肌肉无力。啤酒中溶质含量低,以及酒精对蛋白水解的抑制作用导致肾脏溶质输送减少。肾脏中溶质不足最终导致继发性稀释性低钠血症,原因是身体多余液体的清除减少。在医院早期发现啤酒狂饮性低钠血症对于仔细管理患者很有必要,以便避免神经方面的后果,因为该综合征有独特的病理生理学。我们报告两例因严重低钠血症就诊于急诊科的病例。在对患者和低钠血症实验室检查进行详细的初步评估后,两例均确诊为啤酒狂饮性低钠血症。考虑到啤酒狂饮性低钠血症综合征独特的病理生理学,对患者进行密切监测并给予适当治疗,以预防任何神经后遗症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1693/5832394/f1de65366a4b/cureus-0009-00000002000-i01.jpg

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