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择期结直肠切除术后在强化康复路径中出现并发症的影响。

The impact of complications after elective colorectal resection within an enhanced recovery pathway.

机构信息

Department of Surgery, Steinberg-Bernstein Centre for Minimally-Invasive Surgery and Innovation, McGill University Health Centre, 1650 Cedar Avenue, E19-125, Montreal, QC, H3G 1A4, Canada.

Section of Colorectal Surgery, Department of Surgery, McGill University Health Centre, Montreal, QC, Canada.

出版信息

Tech Coloproctol. 2018 Mar;22(3):191-199. doi: 10.1007/s10151-018-1761-x. Epub 2018 Mar 5.

Abstract

BACKGROUND

Despite the implementation of enhanced recovery pathways (ERP), morbidity following colorectal surgery remains high. The aim of the present study was to estimate the impact of postoperative complications on excess hospital length of stay (LOS) in patients undergoing elective colorectal resection.

METHODS

A retrospective study of patients undergoing elective colorectal surgery at a single institution from 2003 to 2010 was performed. Patients managed by an ERP were compared to conventional care (CC), matched by propensity score radius matching. Complications were defined a priori. Excess (independent effect on LOS from multivariate analysis) and attributable (absolute number of additional bed days) LOS of common postoperative complications determined the impact of complications on bed utilization. Multivariate analysis was performed using multiple linear regression.

RESULTS

A total of 810 propensity-score-matched patients were included (ERP = 472, CC = 338). Complications were significantly lower in the ERP group compared to the CC group (20 vs. 31%, p < 0.001). Median LOS decreased from 7 days in the CC group to 5 days in the ERP group [adjusted decrease in mean LOS of 2.8 days (95% CI 0.8, 4.8)]. Anastomotic leak, myocardial infarction and C. difficile infection had the highest excess LOS for both the ERP and CC groups. However, impaired gastrointestinal function had a higher impact on the absolute number of hospital bed days in the ERP group, as high as anastomotic leak (72.7 vs. 73.5 days respectively), while in the CC group the impact of gastrointestinal dysfunction was less of that of anastomotic leak (50.6 vs. 78.9 days respectively).

CONCLUSIONS

In the setting of an ERP, postoperative complications have significant impact on total bed utilization. Impaired gastrointestinal function, given its high incidence, accounted for almost the same number of additional hospital bed days as anastomotic leak in the ERP group and is a target for quality improvement.

摘要

背景

尽管实施了加速康复路径(ERP),但结直肠手术后的发病率仍然很高。本研究旨在评估术后并发症对择期结直肠切除术患者住院时间延长的影响。

方法

对 2003 年至 2010 年在一家机构接受择期结直肠手术的患者进行回顾性研究。ERP 管理的患者与常规护理(CC)进行比较,通过倾向评分半径匹配进行匹配。并发症预先定义。确定常见术后并发症的超额(多元分析中对 LOS 的独立影响)和归因(额外床位天数的绝对数量)LOS,以确定并发症对床位利用的影响。使用多元线性回归进行多变量分析。

结果

共纳入 810 例倾向评分匹配患者(ERP=472,CC=338)。ERP 组的并发症明显低于 CC 组(20% vs. 31%,p<0.001)。CC 组的中位 LOS 从 7 天降至 ERP 组的 5 天[调整后的平均 LOS 降低 2.8 天(95%CI 0.8,4.8)]。吻合口漏、心肌梗死和艰难梭菌感染在 ERP 和 CC 组的超额 LOS 最高。然而,胃肠道功能障碍对 ERP 组的住院床位天数绝对数的影响更大,与吻合口漏相当(分别为 72.7 天和 73.5 天),而在 CC 组,胃肠道功能障碍的影响小于吻合口漏(分别为 50.6 天和 78.9 天)。

结论

在 ERP 环境下,术后并发症对总床位利用率有显著影响。胃肠道功能障碍的发生率很高,在 ERP 组中与吻合口漏造成的额外住院天数几乎相同,是质量改进的目标。

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