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法国猫白内障的流行病学与临床表现:268例回顾性研究

Epidemiology and clinical presentation of feline cataracts in france: A retrospective study of 268 cases.

作者信息

Guyonnet Alexandre, Donzel Elise, Bourguet Aurélie, Chahory Sabine

机构信息

Unité d'Ophtalmologie, Ecole Nationale Vétérinaire d'Alfort, CHUVA, Maisons-Alfort, France.

出版信息

Vet Ophthalmol. 2019 Mar;22(2):116-124. doi: 10.1111/vop.12567. Epub 2018 Mar 6.

Abstract

OBJECTIVE

To describe the epidemiology and the clinical presentation of cataracts in a population of cats in France.

PROCEDURES

A review of medical records of cats presented to the Ophthalmology Unit of the National Veterinary School of Alfort between January 2010 and June 2017 was carried out to identify cats affected by cataracts. The signalment of affected cats, medical history, etiology of cataract, age of onset, stage of development, location of opacities, and concurrent ocular lesions were evaluated.

RESULTS

Of 2054 cats which were presented to the Ophthalmology Unit of the National Veterinary School of Alfort during the study period, 268 (383 eyes) were diagnosed with a cataract (13%; CI [11.3-14.7]). The median age of all cats affected by cataract was 9.5 years (range: 0.1-18.6 years). Eighteen breeds were represented. The recorded causes of cataract were uveitis (35.8%), congenital (15.7%), aging (10.8%), presumed hereditary (8.2%), trauma (7.8%), lens luxation (3.3%), glaucoma (1.5%) and diabetes mellitus (0.4%). In 16.4% of the cases, the etiology could not be determined. The domestic short-hair was significantly overrepresented in cats with uveitis-related cataract (P < .001). The most common ocular lesions associated with cataracts were lens subluxation or luxation (17.8%), glaucoma (14.9%), and retinal detachment (4.4%). Lens subluxation/luxation and glaucoma were also significantly associated with uveitis-related cataract (P < .001).

CONCLUSIONS

In a French population of referred cats, 13% were affected by cataract. The main causes identified were anterior uveitis, congenital, and aging. Lens subluxation/luxation and glaucoma were associated with uveitis-related cataract.

摘要

目的

描述法国猫群中白内障的流行病学情况及临床表现。

程序

对2010年1月至2017年6月间送至阿尔福特国家兽医学院眼科的猫的病历进行回顾,以确定患白内障的猫。评估患猫的特征、病史、白内障病因、发病年龄、发育阶段、混浊部位及并发眼部病变。

结果

在研究期间送至阿尔福特国家兽医学院眼科的2054只猫中,268只(383只眼)被诊断患有白内障(13%;可信区间[11.3 - 14.7])。所有患白内障猫的中位年龄为9.5岁(范围:0.1 - 18.6岁)。涉及18个品种。记录的白内障病因有葡萄膜炎(35.8%)、先天性(15.7%)、衰老(10.8%)、推测为遗传性(8.2%)、外伤(7.8%)、晶状体脱位(3.3%)、青光眼(1.5%)和糖尿病(0.4%)。在16.4%的病例中,病因无法确定。在与葡萄膜炎相关的白内障猫中,家猫短毛品种显著居多(P <.001)。与白内障相关的最常见眼部病变是晶状体半脱位或脱位(17.8%)、青光眼(14.9%)和视网膜脱离(4.4%)。晶状体半脱位/脱位和青光眼也与葡萄膜炎相关的白内障显著相关(P <.001)。

结论

在法国转诊猫群中,13%患白内障。确定的主要病因是前葡萄膜炎、先天性和衰老。晶状体半脱位/脱位和青光眼与葡萄膜炎相关的白内障有关。

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