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猫白内障的患病率:对2000只正常动物、50只糖尿病猫和100只脱水危机后的猫进行横断面研究的结果。

Prevalence of feline cataract: results of a cross-sectional study of 2000 normal animals, 50 cats with diabetes and one hundred cats following dehydrational crises.

作者信息

Williams David L, Heath M Fred

机构信息

Queen's Veterinary School Small Animal Hospital, University of Cambridge, Madingley Road, Cambridge, England, CB3 0ES, UK.

出版信息

Vet Ophthalmol. 2006 Sep-Oct;9(5):341-9. doi: 10.1111/j.1463-5224.2006.00497.x.

Abstract

OBJECTIVE

In this study 2000 normal cats, 50 cats with diabetes and 100 cats with a history of dehydrational crises were examined ophthalmoscopically to determine presence of cataract.

MATERIALS AND METHODS

The cats examined were predominantly from veterinary hospital populations but also from re-homing facilities and breeding catteries. Prevalence of cataract was determined for different age groups (year cohorts). The age at which prevalence of cataract was 50% (C(50)) was determined indirectly from a fitted prevalence curve as previously described. C(50) was determined for animals of different genders and different breeds as well as for those with diabetes and histories of dehydrational episodes related to chronic renal failure, chronic vomiting or chronic diarrhea.

RESULTS

The mean +/- standard deviation of C(50) for all normal cats in the study was 12.7 +/- 3.4 years. All cats over 17.5 years were affected by some degree of lens opacity. C(50) for cats with diabetes was 5.6 +/- 1.9 years (significantly different from normal cats at P < 0.0001). For cats with a history of dehydrational crises C(50) was 9.9 +/- 2.5 (difference from normal cats nearing statistical significance at P = 0.06).

CONCLUSIONS

The study yields novel findings regarding the prevalence of age-related cataract in normal cats together with cats with diabetes and history of previous dehydrational episodes in which prevalence of cataract is increased.

摘要

目的

本研究对2000只正常猫、50只患有糖尿病的猫和100只曾有脱水危象病史的猫进行了检眼镜检查,以确定白内障的存在情况。

材料与方法

所检查的猫主要来自兽医医院,但也有来自重新安置机构和繁殖猫舍的。确定了不同年龄组(年龄队列)白内障的患病率。如前所述,通过拟合患病率曲线间接确定白内障患病率为50%(C(50))时的年龄。确定了不同性别、不同品种的动物以及患有糖尿病和与慢性肾衰竭、慢性呕吐或慢性腹泻相关的脱水发作病史的动物的C(50)。

结果

本研究中所有正常猫的C(50)的平均值±标准差为12.7±3.4岁。所有17.5岁以上的猫都受到了一定程度的晶状体混浊影响。患有糖尿病的猫的C(50)为5.6±1.9岁(与正常猫相比差异显著,P<0.0001)。有脱水危象病史的猫的C(50)为9.9±2.5(与正常猫的差异接近统计学显著性,P = 0.06)。

结论

该研究得出了关于正常猫以及患有糖尿病和既往有脱水发作病史(白内障患病率增加)的猫中年龄相关性白内障患病率的新发现。

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