Yi Y, Shun-Xiang C, Zheng-Wen H E, Bo L I, You-Bin W, Zhen T U, Zhao-Gang X U, Hui H E, Bo X
Institute of Schistosomiasis Control, Hubei Center for Disease Control and Prevention, Wuhan 430079, China.
Institute of Schistosomiasis Control, Gong'an Center for Disease Control and Prevention, Hubei Province, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2017 Jul 27;29(4):416-419. doi: 10.16250/j.32.1374.2016269.
To evaluate the molluscicidal effect of suspension concentrate of niclosamide ethanolamine salt (SCNE) against snails in laboratory and field. The experiment of SCNE against the snails by using the immersing and spraying methods was performed in laboratory and field, with control groups of wettable powder of niclosamide ethanolamine salt (WPN). In the laboratory, LC of SCNE for 24, 48 h and 72 h by using the immersion method were 0.092 6, 0.062 9 mg/L and 0.054 9 mg/L, respectively. The mortality rates of snails for 24, 48 h and 72 h by using the immersion method were all 100% with the concentrations of 0.25 mg/L. The mortality rates of snails were all 100% while spraying SCNE for 3 d in the laboratory with the concentrations of 0.25 g/m. In Jiangling County, except 0.5 g/m SCNE immersing the snails for 24 h, the mortality rates of snails by using SCNE with the immersing method were all 100%. While the concentration of SCNE was 0.5 g/m or above, the mortality rates were all 100% after the use of it with the immersion method for 2 d in Gong'an County. In Jiangling County, the mortality rates of snails by using SCNE 0.5 g/m for 1 d, 3 d, and 7 d with the spraying method were 87.5%, 92.82% and 97.40% respectively. While the concentration of SCNE was 0.5 g/m, the mortality rates were 85.94%, 86.78% and 94.21% respectively after the use of it with the spraying method for 1 d, 3 d, 7 d in Gong'an County, and the molluscicidal effect of SCNE (1.0 g/m) was higher than that of WPN. SCNE has a high molluscicidal effect in the laboratory and field, and it is a novel and simple formulation of niclosamide.
评估氯硝柳胺乙醇胺盐悬浮剂（SCNE）在实验室和现场对钉螺的杀螺效果。采用浸杀法和喷洒法，在实验室和现场进行SCNE对钉螺的试验，并设置氯硝柳胺乙醇胺盐可湿性粉剂（WPN）对照组。在实验室，浸杀法中SCNE作用24、48和72 h的LC分别为0.092 6、0.062 9 mg/L和0.054 9 mg/L。浓度为0.25 mg/L时，浸杀法作用24、48和72 h钉螺死亡率均为100%。在实验室喷洒SCNE 3 d，浓度为0.25 g/m时钉螺死亡率均为100%。在江陵县，除0.5 g/m SCNE浸杀钉螺24 h外，浸杀法使用SCNE钉螺死亡率均为100%。在公安县，SCNE浓度为0.5 g/m及以上，浸杀法作用2 d后钉螺死亡率均为100%。在江陵县，喷洒法使用0.5 g/m SCNE 1、3和7 d钉螺死亡率分别为87.5%、92.82%和97.40%。在公安县，喷洒法使用浓度为0.5 g/m SCNE 1、3和7 d钉螺死亡率分别为85.94%、86.78%和94.21%，且SCNE（1.0 g/m）的杀螺效果高于WPN。SCNE在实验室和现场均具有较高的杀螺效果，是氯硝柳胺一种新颖且简便的剂型。
