Birla Rodica, Hoara Petre, Caragui Andrei, Cristian Marica, Constantinoiu Silviu
Chirurgia (Bucur). 2018 Jan-Feb;113(1):38-45. doi: 10.21614/chirurgia.113.1.38.
Adenocarcinoma of the gastroesophageal junction is more common in the West. Preoperative chemotherapy or chemoradiotherapy is performed for locally advanced disease. Recent studies are suggesting higher rates of curative resection and reduced rates of local recurrence in patients with neoadjuvant combination of chemotherapy and radiation therapy. The role of targeted agents in neoadjuvant therapy is under investigation.
胃食管交界腺癌在西方更为常见。对于局部晚期疾病，会进行术前化疗或放化疗。最近的研究表明，新辅助化疗与放疗联合治疗的患者，其根治性切除率更高，局部复发率更低。靶向药物在新辅助治疗中的作用正在研究中。
