Poison Information Center of the Federal District, Heath Department of the Government of Federal District, Brasilia, DF, Brazil.
Laboratory of Toxicology, Department of Pharmaceutical Sciences, University of Brasilia, Brasilia, DF, Brazil.
J Public Health (Oxf). 2019 Mar 1;41(1):203-211. doi: 10.1093/pubmed/fdy008.
Poisoning is a worldwide public health problem that involves individuals of all ages and a wide range of chemicals. This study investigated the data from two health information systems to characterize poisoning events in the Federal District (DF), Brazil.
Data related to the period from 2009 to 2013 were obtained from the poison information center (Centro de Informação Toxicológica, CIT) and the Notifiable Diseases Information System (Sistema Nacional de Agravos de Notificação, SINAN) of the DF.
A total of 3622 cases were reported to CIT-DF and 5702 cases to SINAN-DF. Most of the cases in CIT-DF (53%) occurred with children up to 9 years old, while this corresponded to 33.9% in SINAN-DF. Unintentional poisoning was the main circumstance involved in the cases. Pharmaceuticals were the main agent (44.3-47.1% of the cases), mainly clonazepan and paracetamol, and pesticides the most fatal (2.4% fatality rate). Out of the 47 fatal cases reported to the systems, only four were reported to both; six cases occurred with children up to 6 years.
Under-reporting and missing information were identified in both systems, but the data were complementary to describe the epidemiology of poisoning cases in the DF.
中毒是一个全球性的公共卫生问题,涉及各个年龄段和各种化学物质。本研究通过调查两个卫生信息系统的数据,对巴西联邦区(DF)的中毒事件进行了特征描述。
本研究从 DF 的中毒信息中心(Centro de Informação Toxicológica,CIT)和法定传染病报告系统(Sistema Nacional de Agravos de Notificação,SINAN)获取了 2009 年至 2013 年的数据。
CIT-DF 共报告了 3622 例中毒事件,SINAN-DF 报告了 5702 例。CIT-DF 中大多数中毒事件(53%)发生在 9 岁以下的儿童中,而 SINAN-DF 中这一比例为 33.9%。中毒的主要原因是意外伤害。药物是最主要的中毒原因(CIT-DF 占 44.3-47.1%,SINAN-DF 占 40.6%),主要是氯硝西泮和扑热息痛,农药中毒的死亡率最高(2.4%)。两个系统共报告了 47 例死亡病例,其中仅有 4 例同时报告,6 例发生在 6 岁以下儿童。
两个系统都存在漏报和信息缺失的情况,但这些数据可以互补,有助于描述 DF 中毒病例的流行病学特征。