• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Acuros CTS: A fast, linear Boltzmann transport equation solver for computed tomography scatter - Part I: Core algorithms and validation.Acuros CTS:一种用于计算机断层扫描散射的快速、线性 Boltzmann 输运方程求解器——第一部分:核心算法和验证。
Med Phys. 2018 May;45(5):1899-1913. doi: 10.1002/mp.12850. Epub 2018 Apr 6.
2
Acuros CTS: A fast, linear Boltzmann transport equation solver for computed tomography scatter - Part II: System modeling, scatter correction, and optimization.Acuros CTS:一种快速、线性的用于计算机断层散射的 Boltzmann 传输方程求解器——第二部分:系统建模、散射校正和优化。
Med Phys. 2018 May;45(5):1914-1925. doi: 10.1002/mp.12849. Epub 2018 Mar 23.
3
A fast, linear Boltzmann transport equation solver for computed tomography dose calculation (Acuros CTD).用于计算机断层扫描剂量计算的快速线性 Boltzmann 传输方程求解器(Acuros CTD)。
Med Phys. 2019 Feb;46(2):925-933. doi: 10.1002/mp.13305. Epub 2018 Dec 24.
4
Validation of a deterministic linear Boltzmann transport equation solver for rapid CT dose computation using physical dose measurements in pediatric phantoms.利用儿童体模中的物理剂量测量验证用于快速 CT 剂量计算的确定性线性 Boltzmann 输运方程求解器。
Med Phys. 2021 Dec;48(12):8075-8088. doi: 10.1002/mp.15301. Epub 2021 Oct 29.
5
Linear Boltzmann equation solver for voxel-level dosimetry in radiopharmaceutical therapy: Comparison with Monte Carlo and kernel convolution.用于放射性药物治疗体素水平剂量学的线性 Boltzmann 方程求解器:与蒙特卡罗和核卷积的比较。
Med Phys. 2024 Aug;51(8):5604-5617. doi: 10.1002/mp.16996. Epub 2024 Mar 4.
6
Impact of bowtie filter and detector collimation on multislice CT scatter profiles: A simulation study.蝴蝶结滤波器和探测器准直对多层螺旋CT散射剖面的影响:一项模拟研究。
Med Phys. 2021 Feb;48(2):852-870. doi: 10.1002/mp.14652. Epub 2020 Dec 23.
7
Validation of a new grid-based Boltzmann equation solver for dose calculation in radiotherapy with photon beams.验证一种新的基于网格的 Boltzmann 方程求解器在光子放射治疗中的剂量计算中的应用。
Phys Med Biol. 2010 Feb 7;55(3):581-98. doi: 10.1088/0031-9155/55/3/002. Epub 2010 Jan 7.
8
Deterministic linear Boltzmann transport equation solver for patient-specific CT dose estimation: Comparison against a Monte Carlo benchmark for realistic scanner configurations and patient models.用于患者特定CT剂量估计的确定性线性玻尔兹曼输运方程求解器:针对实际扫描仪配置和患者模型与蒙特卡罗基准的比较。
Med Phys. 2020 Dec;47(12):6470-6483. doi: 10.1002/mp.14494. Epub 2020 Oct 20.
9
Patient-specific scatter correction in clinical cone beam computed tomography imaging made possible by the combination of Monte Carlo simulations and a ray tracing algorithm.通过蒙特卡罗模拟和光线追踪算法的结合,实现了临床锥形束计算机断层摄影成像中的患者特异性散射校正。
Acta Oncol. 2013 Oct;52(7):1477-83. doi: 10.3109/0284186X.2013.813641. Epub 2013 Jul 23.
10
Spatial frequency spectrum of the x-ray scatter distribution in CBCT projections.CBCT 投影中 X 射线散射分布的空间频谱。
Med Phys. 2013 Nov;40(11):111901. doi: 10.1118/1.4822484.

引用本文的文献

1
Super-resolution CBCT on a new generation flat panel imager of a C-arm gantry linear accelerator.基于C型臂龙门直线加速器新一代平板探测器的超分辨率锥形束CT
Med Phys. 2025 Jul;52(7):e18000. doi: 10.1002/mp.18000.
2
Localization accuracy of 6-second CBCT for lung IGRT with various breathing patterns.6秒CBCT在不同呼吸模式下用于肺部图像引导放射治疗的定位准确性。
J Appl Clin Med Phys. 2025 Jul;26(7):e70130. doi: 10.1002/acm2.70130. Epub 2025 May 29.
3
Multi-institutional study on image quality for a novel CBCT solution on O-ring linac.关于新型O型环直线加速器CBCT解决方案图像质量的多机构研究。
J Appl Clin Med Phys. 2025 Jun;26(6):e70023. doi: 10.1002/acm2.70023. Epub 2025 Mar 6.
4
Development of an automated CBCT-based simulation-free platform for expedited palliative radiotherapy on a conventional linear accelerator.基于锥形束CT(CBCT)开发一个无需模拟的自动化平台,用于在传统直线加速器上快速进行姑息性放疗。
J Appl Clin Med Phys. 2025 Apr;26(4):e14612. doi: 10.1002/acm2.14612. Epub 2024 Dec 23.
5
Assessment of clinical feasibility:offline adaptive radiotherapy for lung cancer utilizing kV iCBCT and UNet++ based deep learning model.临床可行性评估:利用千伏级内置锥形束CT(kV iCBCT)和基于UNet++的深度学习模型对肺癌进行离线自适应放疗。
J Appl Clin Med Phys. 2025 Feb;26(2):e14582. doi: 10.1002/acm2.14582. Epub 2024 Nov 29.
6
A radiation therapy platform to enable upright cone beam computed tomography and future upright treatment on existing photon therapy machines.一种放射治疗平台,可在现有光子治疗机上实现直立式锥形束计算机断层扫描及未来的直立式治疗。
Med Phys. 2025 Feb;52(2):1133-1145. doi: 10.1002/mp.17523. Epub 2024 Nov 18.
7
Monte Carlo methods for medical imaging research.用于医学成像研究的蒙特卡罗方法。
Biomed Eng Lett. 2024 Sep 5;14(6):1195-1205. doi: 10.1007/s13534-024-00423-x. eCollection 2024 Nov.
8
A joint learning framework for multisite CBCT-to-CT translation using a hybrid CNN-transformer synthesizer and a registration network.一种使用混合卷积神经网络-Transformer合成器和配准网络的多站点CBCT到CT转换的联合学习框架。
Front Oncol. 2024 Aug 8;14:1440944. doi: 10.3389/fonc.2024.1440944. eCollection 2024.
9
Evaluation of knowledge-based planning models for male pelvic CBCT-based online adaptive radiotherapy on conventional linear accelerators.基于知识的计划模型在常规线性加速器上基于男性骨盆 CBCT 的在线自适应放射治疗中的评估。
J Appl Clin Med Phys. 2024 Sep;25(9):e14464. doi: 10.1002/acm2.14464. Epub 2024 Jul 19.
10
Pelvic target volume inter-fractional motion during radiotherapy for cervical cancer with daily iterative cone beam computed tomography.宫颈癌放疗中每日迭代锥形束 CT 时的骨盆靶区分次内运动。
Radiat Oncol. 2024 Apr 15;19(1):48. doi: 10.1186/s13014-024-02438-1.

本文引用的文献

1
Acuros CTS: A fast, linear Boltzmann transport equation solver for computed tomography scatter - Part II: System modeling, scatter correction, and optimization.Acuros CTS:一种快速、线性的用于计算机断层散射的 Boltzmann 传输方程求解器——第二部分:系统建模、散射校正和优化。
Med Phys. 2018 May;45(5):1914-1925. doi: 10.1002/mp.12849. Epub 2018 Mar 23.
2
Optimal combination of anti-scatter grids and software correction for CBCT imaging.锥形束 CT 成像中防散射格栅与软件校正的最佳组合。
Med Phys. 2017 Sep;44(9):4437-4451. doi: 10.1002/mp.12385. Epub 2017 Aug 2.
3
Analytic image reconstruction from partial data for a single-scan cone-beam CT with scatter correction.基于单次扫描锥束CT的部分数据并带有散射校正的解析图像重建
Med Phys. 2015 Nov;42(11):6625-40. doi: 10.1118/1.4933423.
4
Implementation of an efficient Monte Carlo calculation for CBCT scatter correction: phantom study.用于CBCT散射校正的高效蒙特卡罗计算的实现:体模研究
J Appl Clin Med Phys. 2015 Jul 8;16(4):216–227. doi: 10.1120/jacmp.v16i4.5393.
5
A practical cone-beam CT scatter correction method with optimized Monte Carlo simulations for image-guided radiation therapy.一种用于图像引导放射治疗的、具有优化蒙特卡罗模拟的实用锥形束CT散射校正方法。
Phys Med Biol. 2015 May 7;60(9):3567-87. doi: 10.1088/0031-9155/60/9/3567. Epub 2015 Apr 10.
6
High-fidelity artifact correction for cone-beam CT imaging of the brain.用于脑部锥形束CT成像的高保真伪影校正
Phys Med Biol. 2015 Feb 21;60(4):1415-39. doi: 10.1088/0031-9155/60/4/1415. Epub 2015 Jan 22.
7
Patient-specific scatter correction for flat-panel detector-based cone-beam CT imaging.基于平板探测器的锥束CT成像的患者特异性散射校正
Phys Med Biol. 2015 Feb 7;60(3):1339-65. doi: 10.1088/0031-9155/60/3/1339. Epub 2015 Jan 16.
8
Efficient scatter distribution estimation and correction in CBCT using concurrent Monte Carlo fitting.使用并发蒙特卡罗拟合在锥形束计算机断层扫描(CBCT)中进行高效散射分布估计与校正。
Med Phys. 2015 Jan;42(1):54-68. doi: 10.1118/1.4903260.
9
A breast-specific, negligible-dose scatter correction technique for dedicated cone-beam breast CT: a physics-based approach to improve Hounsfield Unit accuracy.用于专用锥形束乳腺CT的一种乳腺特异性、低剂量散射校正技术:一种基于物理的提高亨氏单位准确性的方法。
Phys Med Biol. 2014 Nov 7;59(21):6487-505. doi: 10.1088/0031-9155/59/21/6487. Epub 2014 Oct 13.
10
Optimizing cone beam CT scatter estimation in egs_cbct for a clinical and virtual chest phantom.在用于临床和虚拟胸部体模的egs_cbct中优化锥形束CT散射估计。
Med Phys. 2014 Jul;41(7):071902. doi: 10.1118/1.4881142.

Acuros CTS:一种用于计算机断层扫描散射的快速、线性 Boltzmann 输运方程求解器——第一部分:核心算法和验证。

Acuros CTS: A fast, linear Boltzmann transport equation solver for computed tomography scatter - Part I: Core algorithms and validation.

机构信息

Varian Medical Systems, Palo Alto, CA, 94304, USA.

出版信息

Med Phys. 2018 May;45(5):1899-1913. doi: 10.1002/mp.12850. Epub 2018 Apr 6.

DOI:10.1002/mp.12850
PMID:29509970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5948176/
Abstract

PURPOSE

To describe Acuros CTS, a new software tool for rapidly and accurately estimating scatter in x-ray projection images by deterministically solving the linear Boltzmann transport equation (LBTE).

METHODS

The LBTE describes the behavior of particles as they interact with an object across spatial, energy, and directional (propagation) domains. Acuros CTS deterministically solves the LBTE by modeling photon transport associated with an x-ray projection in three main steps: (a) Ray tracing photons from the x-ray source into the object where they experience their first scattering event and form scattering sources. (b) Propagating photons from their first scattering sources across the object in all directions to form second scattering sources, then repeating this process until all high-order scattering sources are computed using the source iteration method. (c) Ray-tracing photons from scattering sources within the object to the detector, accounting for the detector's energy and anti-scatter grid responses. To make this process computationally tractable, a combination of analytical and discrete methods is applied. The three domains are discretized using the Linear Discontinuous Finite Elements, Multigroup, and Discrete Ordinates methods, respectively, which confer the ability to maintain the accuracy of a continuous solution. Furthermore, through the implementation in CUDA, we sought to exploit the parallel computing capabilities of graphics processing units (GPUs) to achieve the speeds required for clinical utilization. Acuros CTS was validated against Geant4 Monte Carlo simulations using two digital phantoms: (a) a water phantom containing lung, air, and bone inserts (WLAB phantom) and (b) a pelvis phantom derived from a clinical CT dataset. For these studies, we modeled the TrueBeam (Varian Medical Systems, Palo Alto, CA) kV imaging system with a source energy of 125 kVp. The imager comprised a 600 μm-thick Cesium Iodide (CsI) scintillator and a 10:1 one-dimensional anti-scatter grid. For the WLAB studies, the full-fan geometry without a bowtie filter was used (with and without the anti-scatter grid). For the pelvis phantom studies, a half-fan geometry with bowtie was used (with the anti-scatter grid). Scattered and primary photon fluences and energies deposited in the detector were recorded.

RESULTS

The Acuros CTS and Monte Carlo results demonstrated excellent agreement. For the WLAB studies, the average percent difference between the Monte Carlo- and Acuros-generated scattered photon fluences at the face of the detector was -0.7%. After including the detector response, the average percent differences between the Monte Carlo- and Acuros-generated scatter fractions (SF) were -0.1% without the grid and 0.6% with the grid. For the digital pelvis simulation, the Monte Carlo- and Acuros-generated SFs agreed to within 0.1% on average, despite the scatter-to-primary ratios (SPRs) being as high as 5.5. The Acuros CTS computation time for each scatter image was ~1 s using a single GPU.

CONCLUSIONS

Acuros CTS enables a fast and accurate calculation of scatter images by deterministically solving the LBTE thus offering a computationally attractive alternative to Monte Carlo methods. Part II describes the application of Acuros CTS to scatter correction of CBCT scans on the TrueBeam system.

摘要

目的

描述 Acuros CTS,这是一种新的软件工具,用于通过确定性求解线性 Boltzmann 输运方程(LBTE)快速准确地估计 X 射线投影图像中的散射。

方法

LBTE 描述了粒子与物体相互作用时在空间、能量和方向(传播)域中的行为。Acuros CTS 通过在三个主要步骤中建模与 X 射线投影相关的光子输运来确定性地求解 LBTE:(a)从 X 射线源追踪光子进入物体,在物体中它们经历第一次散射事件并形成散射源。(b)在各个方向上从第一个散射源传播光子穿过物体,形成第二个散射源,然后使用源迭代方法重复此过程,直到计算出所有高阶散射源。(c)从物体内的散射源追踪光子到探测器,同时考虑探测器的能量和反散射栅格响应。为了使这个过程在计算上可行,应用了分析和离散方法的组合。三个域分别使用线性不连续有限元、多群和离散坐标方法进行离散化,这使得能够保持连续解的准确性。此外,通过在 CUDA 中的实现,我们试图利用图形处理单元(GPU)的并行计算能力来实现临床应用所需的速度。使用两个数字体模:(a)包含肺、空气和骨骼插入物的水体模(WLAB 体模)和(b)源自临床 CT 数据集的骨盆体模,对 Acuros CTS 进行了与 Geant4 蒙特卡罗模拟的验证。对于这些研究,我们用 125 kVp 的源能量模拟了 TrueBeam(Varian Medical Systems,Palo Alto,CA)kV 成像系统。成像仪由 600 µm 厚的碘化铯(CsI)闪烁体和 10:1 一维反散射栅格组成。对于 WLAB 研究,使用了全扇几何形状(带或不带蝴蝶结滤光片),而没有使用反散射栅格。对于骨盆体模研究,使用带有蝴蝶结的半扇几何形状(带反散射栅格)。记录了探测器中沉积的散射和初级光子的通量和能量。

结果

Acuros CTS 和蒙特卡罗的结果表现出极好的一致性。对于 WLAB 研究,蒙特卡罗和 Acuros 生成的散射光子通量在探测器表面的平均百分比差异为-0.7%。在包括探测器响应后,蒙特卡罗和 Acuros 生成的散射分数(SF)的平均百分比差异在没有栅格的情况下为-0.1%,在有栅格的情况下为 0.6%。对于数字骨盆模拟,尽管散射与初级比(SPR)高达 5.5,但蒙特卡罗和 Acuros 生成的 SF 平均相差在 0.1%以内。使用单个 GPU,每个散射图像的 Acuros CTS 计算时间约为 1 秒。

结论

Acuros CTS 通过确定性求解 LBTE 实现了散射图像的快速准确计算,从而为蒙特卡罗方法提供了一种具有吸引力的计算替代方案。第二部分描述了 Acuros CTS 在 TrueBeam 系统上对锥形束 CT 扫描的散射校正中的应用。