Department of Clinical Nutrition, Medical University of Gdansk, 80-211 Gdańsk, Poland.
Clinic of Cardiac and Vascular Surgery, Medical University of Gdansk, 80-211 Gdansk, Poland.
Nutrients. 2018 Mar 5;10(3):304. doi: 10.3390/nu10030304.
Severe aortic stenosis (AS) is associated with the reduction of muscle mass and may be associated with deterioration of nutritional status. Furthermore, malnourished cardiac patients are characterized by a higher risk of postoperative complications and mortality. The aim of this study was the evaluation and comparison of nutritional status, appetite and body composition in older people with severe aortic stenosis before aortic valve replacement and healthy elderly volunteers. One hundred and one patients, aged >65 years old with severe AS were included in the study. Nutritional status was assessed. Body composition was estimated using bioelectrical impedance analysis. Concentrations of albumin, prealbumin, triglycerides, total cholesterol and C-reactive protein were measured, and a complete blood count was done. About 40% of AS patients were at risk of malnutrition. They had decreased hand grip strength and they lost more body mass than the control group. Malnourished AS patients were older, had lower body mass indexes (BMIs) and lower aortic valve areas in comparison to well-nourished patients. Older AS patients, like their peers, show excessive body mass and, at the same time, the features of malnutrition. They have additional factors such as unintentional weight lost and decreased muscle strength which may be associated with worse outcomes.
严重的主动脉瓣狭窄(AS)与肌肉质量减少有关,并且可能与营养状况恶化有关。此外,营养不良的心脏患者术后并发症和死亡率较高。本研究的目的是评估和比较主动脉瓣置换术前后老年严重主动脉瓣狭窄患者与健康老年志愿者的营养状况、食欲和身体成分。研究纳入了 101 名年龄>65 岁的严重 AS 患者。评估营养状况。使用生物电阻抗分析估计身体成分。测量白蛋白、前白蛋白、甘油三酯、总胆固醇和 C 反应蛋白的浓度,并进行全血细胞计数。大约 40%的 AS 患者有营养不良的风险。他们的握力下降,比对照组丢失更多的体重。与营养良好的患者相比,营养不良的 AS 患者年龄更大,体重指数(BMI)更低,主动脉瓣面积更小。与同龄人一样,老年 AS 患者表现出超重,同时存在营养不良的特征。他们还有其他一些因素,如非故意体重减轻和肌肉力量下降,这可能与预后更差有关。