Khan Jahidur Rahman, Islam Md Mazharul, Awan Nabil, Muurlink Olav
Institute of Statistical Research and Training, University of Dhaka, Dhaka, Bangladesh.
Department of Biostatistics, University of Pittsburgh, Pittsburgh, USA.
BMC Pediatr. 2018 Mar 6;18(1):100. doi: 10.1186/s12887-018-1068-0.
Low birth weight (LBW) remains a leading global cause of childhood morbidity and mortality. This study leverages a large national survey to determine current prevalence and socioeconomic, demographic and heath related factors associated with LBW in Bangladesh.
Data from the Multiple Indicator Cluster Survey (MICS) 2012-13 of Bangladesh were analyzed. A total of 2319 women for whom contemporaneous birth weight data was available and who had a live birth in the two years preceding the survey were sampled for this study. However, this analysis only was able to take advantage of 29% of the total sample with 71% missing birth weight for newborns. The indicator, LBW (< 2500 g) of infants, was examined as the outcome variable in association with different socioeconomic, demographic and health-related covariates. Mixed-effects logistic regression was performed to identify possible factors related to LBW.
In the selected sub-sample, about 20% of infants were born with LBW, with lowest rates observed in Rajshahi (11%) and highest rates in Rangpur (28%). Education of mothers (adjusted odds ratio [AOR] 0.52, 95% confidence interval [CI] 0.39-0.68 for secondary or higher educated mother) and poor antenatal care (ANC) (AOR 1.40, 95% CI 1.04-1.90) were associated with LBW after adjusting for mother's age, parity and cluster effects. Mothers from wealthier families were less likely to give birth to an LBW infant. Further indicators that wealth continues to play a role in LBW were that place of delivery, ANC and delivery assistance by quality health workers were significantly associated with LBW. However there has been a notable fall in LBW prevalence in Bangladesh since the last comparable survey (prevalence 36%), and an evidence of possible elimination of rural/urban disparities.
Low birth weight remains associated with key indicators not just of maternal poverty (notably adequate maternal education) but also markers of structural poverty in health care (notably quality ANC). Results based on this sub-sample indicate LBW is still a public health concern in Bangladesh and an integrated effort from all stakeholders should be continued and interventions based on the study findings should be devised to further reduce the risk of LBW.
低出生体重仍是全球儿童发病和死亡的主要原因。本研究利用一项大型全国性调查来确定孟加拉国低出生体重的当前患病率以及与低出生体重相关的社会经济、人口和健康相关因素。
对孟加拉国2012 - 2013年多指标类集调查(MICS)的数据进行分析。本研究抽取了2319名有同期出生体重数据且在调查前两年内有活产的妇女作为样本。然而,该分析仅能利用总样本的29%,因为71%的新生儿出生体重数据缺失。将婴儿低出生体重(<2500克)这一指标作为结果变量,与不同的社会经济、人口和健康相关协变量进行关联分析。采用混合效应逻辑回归来确定与低出生体重相关的可能因素。
在选定的子样本中,约20%的婴儿出生时低体重,其中拉杰沙希地区的发生率最低(11%),朗布尔地区最高(28%)。在对母亲年龄、胎次和聚类效应进行调整后,母亲的教育程度(受过中等或更高教育的母亲,调整后的优势比[AOR]为0.52,95%置信区间[CI]为0.39 - 0.68)和产前保健(ANC)不佳(AOR为1.40,95%CI为1.04 - 1.90)与低出生体重相关。来自较富裕家庭的母亲生下低体重婴儿的可能性较小。财富继续在低出生体重中发挥作用的进一步指标是分娩地点、产前保健以及高质量卫生工作者提供的分娩协助与低出生体重显著相关。然而,自上次可比调查(患病率为36%)以来,孟加拉国的低出生体重患病率已显著下降,并且有证据表明农村/城市差距可能消除。
低出生体重不仅与孕产妇贫困的关键指标(特别是母亲受教育程度不足)有关,还与医疗保健方面的结构性贫困指标(特别是高质量的产前保健)有关。基于该子样本的结果表明,低出生体重在孟加拉国仍然是一个公共卫生问题,所有利益相关者应继续做出综合努力,并应根据研究结果制定干预措施,以进一步降低低出生体重的风险。