• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Fatal Acute Liver Failure With Intravenous Amiodarone: A Case Report and Literature Review.

作者信息

Gayam Vijay, Khalid Mazin, Dahal Sumit, Garlapati Pavani, Gill Arshpal, Alex Ragin, Mansour Mohammad

机构信息

Interfaith Medical Center, 1545 Atlantic Ave, Brooklyn, NY 11213, USA.

American University of Antigua, Jabberwock Rd, Osbourn, Antigua and Barbuda.

出版信息

Gastroenterology Res. 2018 Feb;11(1):62-63. doi: 10.14740/gr911w. Epub 2018 Feb 23.

DOI:10.14740/gr911w
PMID:29511409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5827905/
Abstract

Amiodarone is a drug which frequently causes elevated transaminases. However, acute liver failure has been rarely reported. Here, we present a case of fatal acute liver failure following the administration of intravenous amiodarone. It is important to be aware of this rare but potentially fatal complication of intravenous amiodarone so that it can be withdrawn immediately at the first sign of hepatic impairment.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce19/5827905/147f8df19f3a/gr-11-062-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce19/5827905/ff76dee270cb/gr-11-062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce19/5827905/147f8df19f3a/gr-11-062-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce19/5827905/ff76dee270cb/gr-11-062-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce19/5827905/147f8df19f3a/gr-11-062-g002.jpg

相似文献

1
Fatal Acute Liver Failure With Intravenous Amiodarone: A Case Report and Literature Review.
Gastroenterology Res. 2018 Feb;11(1):62-63. doi: 10.14740/gr911w. Epub 2018 Feb 23.
2
Concomitant Acute Hepatic Failure and Renal Failure Induced by Intravenous Amiodarone: A Case Report and Literature Review.静脉注射胺碘酮所致急性肝衰竭和肾衰竭并存：一例报告及文献综述
Gastroenterology Res. 2020 Feb;13(1):40-43. doi: 10.14740/gr1254. Epub 2020 Feb 1.
3
Fatal amiodarone-induced hepatotoxicity: a case report and literature review.胺碘酮所致致命性肝毒性：1例病例报告及文献综述
Int J Clin Pharmacol Ther. 2008 Feb;46(2):96-101. doi: 10.5414/cpp46096.
4
Hepatotoxicity during rapid intravenous loading with amiodarone: Description of three cases and review of the literature.胺碘酮快速静脉负荷给药期间的肝毒性：三例病例描述及文献综述
Crit Care Med. 2005 Jan;33(1):128-34; discussion 245-6. doi: 10.1097/01.ccm.0000151048.72393.44.
5
Acute liver injury after intravenous amiodarone: a case report.静脉用胺碘酮致急性肝损伤：1 例报告。
Am J Emerg Med. 2011 Sep;29(7):843.e5-6. doi: 10.1016/j.ajem.2010.03.035. Epub 2010 Sep 25.
6
Acute hepatitis after amiodarone infusion.胺碘酮输注后急性肝炎。
World J Clin Cases. 2015 Oct 16;3(10):900-3. doi: 10.12998/wjcc.v3.i10.900.
7
A Rare Case of Intravenous Amiodarone Toxicity.静脉注射胺碘酮中毒的罕见病例。
Cureus. 2022 Aug 13;14(8):e27958. doi: 10.7759/cureus.27958. eCollection 2022 Aug.
8
Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle?静脉注射胺碘酮所致的早期急性肝炎：是溶媒的毒性作用？
Gut. 1993 Apr;34(4):565-6. doi: 10.1136/gut.34.4.565.
9
[Early-onset acute toxic hepatitis induced by intravenous amiodarone administration].[静脉注射胺碘酮所致早发性急性中毒性肝炎]
Gastroenterol Hepatol. 2002 Jun-Jul;25(6):392-4.
10
Acute amiodarone-induced hepatitis.急性胺碘酮诱发的肝炎。
Hepatogastroenterology. 1991 Feb;38(1):71-4.

引用本文的文献

1
Dose study of rosuvastatin calcium in the treatment of coronary heart disease and hyperlipidemia.瑞舒伐他汀钙治疗冠心病和高脂血症的剂量研究。
Am J Transl Res. 2023 May 15;15(5):3403-3409. eCollection 2023.
2
Therapeutic evaluation of rosuvastatin on lipids and endothelial cell functionalities in coronary artery lesions coinciding with hyperlipidemia.瑞舒伐他汀对合并高脂血症的冠状动脉病变中血脂及内皮细胞功能的治疗评估
Am J Transl Res. 2023 May 15;15(5):3152-3161. eCollection 2023.
3
Case 9: A 62-Year-Old Woman With Jaundice and General Weakness.

本文引用的文献

1
Fatal acute liver failure after intravenous amiodarone administration.静脉注射胺碘酮后发生致命性急性肝衰竭。
J Formos Med Assoc. 2015 Mar;114(3):294-6. doi: 10.1016/j.jfma.2013.07.011. Epub 2013 Aug 14.
2
Low-dose amiodarone-induced fatal liver failure.
Drug Chem Toxicol. 2013 Apr;36(2):261-2. doi: 10.3109/01480545.2011.653489. Epub 2012 Feb 23.
3
Acute amiodarone liver toxicity likely due to ischemic hepatitis.急性胺碘酮肝毒性可能归因于缺血性肝炎。
Isr Med Assoc J. 2011 Dec;13(12):748-52.
病例9：一名62岁黄疸及全身乏力的女性。
J Korean Med Sci. 2023 Apr 10;38(14):e105. doi: 10.3346/jkms.2023.38.e105.
4
Amiodarone-induced hepatotoxicity - quantitative measurement of iodine density in the liver using dual-energy computed tomography: Three case reports.胺碘酮所致肝毒性——使用双能计算机断层扫描定量测量肝脏碘密度：三例病例报告
World J Clin Cases. 2020 Oct 26;8(20):4958-4965. doi: 10.12998/wjcc.v8.i20.4958.
5
Hyperammonemic Encephalopathy and Lipid Dysmetabolism in a Critically Ill Patient After a Short Course of Amiodarone.
J Crit Care Med (Targu Mures). 2019 Nov 27;5(4):161-165. doi: 10.2478/jccm-2019-0026. eCollection 2019 Oct.
4
Rapidly fatal acute amiodarone hepatitis occurring in the context of multiple organ failure.
Int J Cardiol. 2003 Oct;91(2-3):245-7. doi: 10.1016/s0167-5273(02)00613-7.
5
Early acute hepatitis with parenteral amiodarone: a toxic effect of the vehicle?静脉注射胺碘酮所致的早期急性肝炎：是溶媒的毒性作用？
Gut. 1993 Apr;34(4):565-6. doi: 10.1136/gut.34.4.565.
6
Hypotensive action of commercial intravenous amiodarone and polysorbate 80 in dogs.市售静脉注射用胺碘酮和聚山梨酯80对犬的降压作用。
J Cardiovasc Pharmacol. 1982 May-Jun;4(3):375-80. doi: 10.1097/00005344-198205000-00006.
7
Acute amiodarone-induced hepatitis.急性胺碘酮诱发的肝炎。
Hepatogastroenterology. 1991 Feb;38(1):71-4.