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职业接触极低频电磁场与脑膜瘤关联性的病例对照研究。

Case-Control Study on Occupational Exposure to Extremely Low-Frequency Electromagnetic Fields and the Association with Meningioma.

机构信息

Department of Oncology, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.

Department of Labour Environment and Safety, Tallinn University of Technology, SOC353 Ehitajate Tee 5, 19086 Tallinn, Estonia.

出版信息

Biomed Res Int. 2018 Jan 3;2018:5912394. doi: 10.1155/2018/5912394. eCollection 2018.

DOI:10.1155/2018/5912394
PMID:29511686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5817292/
Abstract

OBJECTIVE

Exposure to extremely low-frequency electromagnetic fields (ELF-EMF) was in 2002 classified as a possible human carcinogen, Group 2B, by the International Agency for Research on Cancer at WHO based on an increased risk for childhood leukemia. In case-control studies on brain tumors during 1997-2003 and 2007-2009 we assessed lifetime occupations in addition to exposure to different agents. The INTEROCC ELF-EMF Job-Exposure Matrix was used for associating occupations with ELF-EMF exposure (T) with meningioma. Cumulative exposure (T-years), average exposure (T), and maximum exposed job (T) were calculated.

RESULTS

No increased risk for meningioma was found in any category. For cumulative exposure in the highest exposure category 8.52+ T years odds ratio (OR) = 0.9, 95% confidence interval (CI) = 0.7-1.2, and linear trend = 0.45 were calculated. No statistically significant risks were found in different time windows.

CONCLUSION

In conclusion occupational ELF-EMF was not associated with an increased risk for meningioma.

摘要

目的

基于接触极低频电磁场(ELF-EMF)会增加儿童白血病的风险,世界卫生组织下属的国际癌症研究机构于 2002 年将其归为 2B 类人类可能致癌物。在 1997-2003 年和 2007-2009 年期间进行的脑肿瘤病例对照研究中,我们评估了一生中的职业,以及接触不同物质的情况。我们使用 INTEROCC ELF-EMF 职业暴露矩阵将职业与 ELF-EMF 暴露(T)与脑膜瘤联系起来。计算了累积暴露(T 年)、平均暴露(T)和最大暴露职业(T)。

结果

在任何类别中,均未发现脑膜瘤风险增加。在最高暴露类别中,累积暴露 8.52+T 年的比值比(OR)为 0.9,95%置信区间(CI)为 0.7-1.2,线性趋势为 0.45。在不同的时间窗口中未发现具有统计学意义的风险。

结论

总之,职业性 ELF-EMF 与脑膜瘤风险增加无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f470/5817292/53900022b7c0/BMRI2018-5912394.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f470/5817292/01cd53e1a21a/BMRI2018-5912394.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f470/5817292/53900022b7c0/BMRI2018-5912394.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f470/5817292/01cd53e1a21a/BMRI2018-5912394.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f470/5817292/53900022b7c0/BMRI2018-5912394.002.jpg

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