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澳大利亚糖尿病患病率:弗里曼特尔糖尿病研究第二阶段的见解

Prevalence of diabetes in Australia: insights from the Fremantle Diabetes Study Phase II.

作者信息

Davis Wendy A, Peters Kirsten E, Makepeace Ashley, Griffiths Shaye, Bundell Christine, Grant Struan F A, Ellard Sian, Hattersley Andrew T, Paul Chubb Stephen A, Bruce David G, Davis Timothy M E

机构信息

Medical School, University of Western Australia, Perth, Western Australia, Australia.

Department of Endocrinology and Diabetes, Fiona Stanley Hospital, Perth, Western Australia, Australia.

出版信息

Intern Med J. 2018 Jul;48(7):803-809. doi: 10.1111/imj.13792.

Abstract

BACKGROUND

Accurate diabetes prevalence estimates are important for health service planning and prioritisation. Available data have limitations, suggesting that the contemporary burden of diabetes in Australia is best assessed from multiple sources.

AIMS

To use systematic active detection of diabetes cases in a postcode-defined urban area through the Fremantle Diabetes Study Phase II (FDS2) to complement other epidemiological and survey data in estimating the national prevalence of diabetes and its types.

METHODS

People with known diabetes in a population of 157 000 were identified (n = 4639) from a variety of sources and those providing informed consent (n = 1668 or 36%) were recruited to the FDS2 between 2008 and 2011. All FDS2 participants were assigned a type of diabetes based on clinical and laboratory (including serological and genetic) features. Data from people identified through the FDS2 were used to complement Australian Health Survey and National Diabetes Services Scheme prevalence estimates (the proportions of people well controlled on no pharmacotherapy and registering with the National Diabetes Services Scheme respectively) in combination with Australian Bureau of Statistics data to generate the prevalence of diabetes in Australia.

RESULTS

Based on data from multiple sources, 4.8% or 1.1 million Australians had diabetes in 2011-2012, of whom 85.8% had type 2 diabetes, 7.9% type 1 diabetes and 6.3% other types (latent autoimmune diabetes of adults, monogenic diabetes and secondary diabetes).

CONCLUSIONS

Approximately 1 in 20 Australians has diabetes. Although most have type 2 diabetes, one in seven has other types that may require more specialised diagnosis and/or management.

摘要

背景

准确估计糖尿病患病率对于卫生服务规划和优先级确定至关重要。现有数据存在局限性,这表明澳大利亚当代糖尿病负担最好从多个来源进行评估。

目的

通过弗里曼特尔糖尿病研究二期(FDS2)在一个以邮政编码定义的城市区域系统地主动检测糖尿病病例,以补充其他流行病学和调查数据,从而估计全国糖尿病及其类型的患病率。

方法

从各种来源确定了15.7万人群中已知患有糖尿病的人(n = 4639),2008年至2011年期间,那些提供知情同意的人(n = 1668或36%)被纳入FDS2。所有FDS2参与者根据临床和实验室(包括血清学和遗传学)特征被分配一种糖尿病类型。通过FDS2确定的人群的数据与澳大利亚统计局的数据相结合,用于补充澳大利亚健康调查和国家糖尿病服务计划患病率估计值(分别为未接受药物治疗但控制良好的人群比例和在国家糖尿病服务计划登记的人群比例),以得出澳大利亚糖尿病的患病率。

结果

基于多个来源的数据,2011 - 2012年有4.8%或110万澳大利亚人患有糖尿病,其中85.8%患有2型糖尿病,7.9%患有1型糖尿病,6.3%患有其他类型(成人隐匿性自身免疫性糖尿病、单基因糖尿病和继发性糖尿病)。

结论

大约每20个澳大利亚人中就有1人患有糖尿病。虽然大多数人患有2型糖尿病,但七分之一的人患有其他类型糖尿病,可能需要更专业的诊断和/或管理。

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