Hasenkam J M, Ostergaard J H, Pedersen E M, Paulsen P K, Nissen T
Life Support Syst. 1986 Oct-Dec;4(4):335-44.
We have developed and improved a method for the continuous on-line registration of cardiac output. By measuring blood velocity with a hot-film anemometer probe in the pulmonary artery, cardiac output can be estimated by gated systolic integration of the velocity signals. The integrated value for a certain period can be converted to a cardiac output proportional value. A thermistor placed next to the velocity probe enables thermodilution measurement of cardiac output, which serves as in vivo and in situ calibration. In this paper an in vitro study of the method applied to pulsatile flow is presented. A good correlation was found between real flow and both the velocity method and the thermodilution method. Fluid temperature and changing stroke volume and/or pulse frequency had minimal influence on accuracy, whereas altered probe position required recalibration for the velocity method but not for the thermodilution method. The advantages of the velocity method for the measurement of cardiac output are: The continuous on-line monitoring of cardiac output. The need for the injection of only very small volumes of cold saline, as the frequency of thermodilution measurements is reduced.
我们已经开发并改进了一种用于连续在线记录心输出量的方法。通过用热膜风速仪探头在肺动脉中测量血流速度,可通过对速度信号进行门控收缩期积分来估计心输出量。某一时间段的积分值可转换为与心输出量成比例的值。置于速度探头旁边的热敏电阻可进行心输出量的热稀释测量,用作体内和原位校准。本文介绍了该方法应用于脉动流的体外研究。发现实际流量与速度法和热稀释法之间具有良好的相关性。流体温度以及改变的搏出量和/或脉搏频率对准确性的影响极小,而探头位置改变时,速度法需要重新校准,热稀释法则不需要。速度法测量心输出量的优点是:可连续在线监测心输出量。由于热稀释测量频率降低,仅需注射极少量冷盐水。