Paulsen P K, Andersen M
Eur Surg Res. 1981;13(5):376-86. doi: 10.1159/000128205.
In order to construct a catheter, capable of monitoring cardiac output, a specially designed double-conical hot-film anemometer probe was fastened at the tip of a Swan-Ganz thermodilution catheter. Common sources of error for most catheter velocity probes include difficult calibration, unknown velocity profile at the point of measurement and unknown position of the probe in this profile. By using mongrel dogs and in order to exclude these sources of error, the intermittent thermodilution method was used to in vitro calibrate the hot-film anemometer, which registered velocity continuously. A mean correlation coefficient between these two methods was found to be 0.886. A mean line of regression between thermodilution (abscissa) and anemometer (ordinate) had a slope of 0.796 +/- 0.223 (+/- SD) and a y-intercept of 24 +/- 14 ml/min/kg. The slope was significantly lower than one (t test, p less than 0.05) and the y-intercept significantly larger than zero (t test, p less than 0.02). As a control of the thermodilution method, electromagnetic flow in the ascending aorta was registered and a mean correlation coefficient of 0.967 found. The hot-film sensor itself can be used as thermodilution method with the hot-film anemometer's continuous registration of velocity.
为构建一种能够监测心输出量的导管，将一个特殊设计的双锥形热膜风速计探头固定在一根Swan - Ganz热稀释导管的尖端。大多数导管速度探头常见的误差来源包括校准困难、测量点处未知的速度分布以及探头在该分布中的未知位置。通过使用杂种犬并为排除这些误差来源，采用间歇热稀释法对热膜风速计进行体外校准，该风速计可连续记录速度。发现这两种方法之间的平均相关系数为0.886。热稀释法（横坐标）和风速计法（纵坐标）之间的平均回归线斜率为0.796±0.223（±标准差），y轴截距为24±14 ml/min/kg。该斜率显著低于1（t检验，p＜0.05），y轴截距显著大于0（t检验，p＜0.02）。作为热稀释法的对照，记录升主动脉中的电磁流量，发现平均相关系数为0.967。热膜传感器本身可作为热稀释法使用，热膜风速计可连续记录速度。
