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儿童和成人重度哮喘的新型疗法。

Novel therapies for severe asthma in children and adults.

作者信息

Delimpoura Vasiliki, Bostantzoglou Clementine, Liu Norrice, Nenna Raffaella

机构信息

7th Respiratory Medicine Dept, "Sotiria" Athens Chest Hospital, Athens, Greece.

Centre for Genomics and Child Health, Blizard Institute, London, UK.

出版信息

Breathe (Sheff). 2018 Mar;14(1):59-62. doi: 10.1183/20734735.018917.

DOI:10.1183/20734735.018917
PMID:29515670
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5831346/
Abstract

http://ow.ly/UWpg30hImQh.

摘要

http://ow.ly/UWpg30hImQh. （此为网址，无法直接翻译，保留原文）

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本文引用的文献

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Personalised medicine in asthma: from curative to preventive medicine.哮喘的个性化医疗：从治愈性医学到预防性医学。
Eur Respir Rev. 2017 Jan 3;26(143). doi: 10.1183/16000617.0010-2016. Print 2017 Jan.
2
Omalizumab reduces bronchial mucosal IgE and improves lung function in non-atopic asthma.奥马珠单抗可降低非过敏性哮喘的支气管黏膜 IgE 并改善肺功能。
Eur Respir J. 2016 Dec;48(6):1593-1601. doi: 10.1183/13993003.01501-2015. Epub 2016 Oct 20.
3
The efficacy and safety of reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: A systematic review and meta-analysis.瑞利珠单抗治疗血嗜酸性粒细胞计数升高的控制不佳哮喘的疗效和安全性：一项系统评价和荟萃分析。
J Asthma. 2017 Apr;54(3):300-307. doi: 10.1080/02770903.2016.1212371. Epub 2016 Jul 19.
4
Treatment response with mepolizumab in severe eosinophilic asthma patients with previous omalizumab treatment.美泊利珠单抗治疗既往使用奥马珠单抗治疗的重度嗜酸性粒细胞性哮喘患者的疗效
Allergy. 2016 Sep;71(9):1335-44. doi: 10.1111/all.12914. Epub 2016 May 24.
5
'Real-life' effectiveness studies of omalizumab in adult patients with severe allergic asthma: systematic review.奥马珠单抗治疗成人重度变应性哮喘的真实世界疗效研究：系统评价。
Allergy. 2016 May;71(5):593-610. doi: 10.1111/all.12815. Epub 2016 Feb 25.
6
Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives.重度过敏性哮喘中的抗IgE治疗、气道炎症与重塑：当前认知与未来展望
Eur Respir Rev. 2015 Dec;24(138):594-601. doi: 10.1183/16000617.00001715.
7
Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials.瑞利珠单抗治疗血嗜酸性粒细胞计数升高的哮喘控制不佳：两项多中心、平行、双盲、随机、安慰剂对照、3 期临床试验结果。
Lancet Respir Med. 2015 May;3(5):355-66. doi: 10.1016/S2213-2600(15)00042-9. Epub 2015 Feb 23.
8
Global burden of asthma among children.全球儿童哮喘负担。
Int J Tuberc Lung Dis. 2014 Nov;18(11):1269-78. doi: 10.5588/ijtld.14.0170.
9
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.美泊利珠单抗在嗜酸性粒细胞性哮喘中的口服糖皮质激素节省作用。
N Engl J Med. 2014 Sep 25;371(13):1189-97. doi: 10.1056/NEJMoa1403291. Epub 2014 Sep 8.
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Mepolizumab treatment in patients with severe eosinophilic asthma.美泊利珠单抗治疗严重嗜酸性粒细胞性哮喘患者。
N Engl J Med. 2014 Sep 25;371(13):1198-207. doi: 10.1056/NEJMoa1403290. Epub 2014 Sep 8.