Suppr超能文献

加纳苏尼亚尼市影响使用磺胺多辛-乙胺嘧啶进行孕期疟疾间歇性预防治疗的因素

Factors influencing uptake of intermittent preventive treatment of malaria in pregnancy using sulphadoxine pyrimethamine in Sunyani Municipality, Ghana.

作者信息

Ibrahim Hajira, Maya Ernest Tei, Issah Kofi, Apanga Paschal Awingura, Bachan Emmanuel George, Noora Charles Lwanga

机构信息

Regional Health Directorate, Upper East Region, Bolgatanga, Ghana.

University of Ghana, Department of Population, Family and Reproductive Health, Accra, Ghana.

出版信息

Pan Afr Med J. 2017 Oct 10;28:122. doi: 10.11604/pamj.2017.28.122.12611. eCollection 2017.

Abstract

INTRODUCTION

Malaria continues to pose a public health challenge in Ghana particularly in pregnant women. Ghana adopted intermittent preventive treatment of malaria in pregnancy policy using sulphadoxine pyrimethamine. Despite its implementation, its coverage still remains low. This study sought to investigate factors that influence the uptake of intermittent preventive treatment of malaria in pregnancy in the Sunyani Municipality.

METHODS

This was a cross sectional study which employed a quantitative method. The study was conducted in five selected facilities in the Sunyani Municipality within the period of January to June 2015. Structured questionnaires were administered to 400 pregnant women randomly sampled from antenatal clinics of selected health facilities. Descriptive, bivariate and multivariate analysis of quantitative data was done using Stata12.

RESULTS

A total of 400 pregnant women at 36 weeks or more gestational age were studied. The study revealed that 98.5% of the pregnant women received at least one (1) dose of sulphadoxine pyrimethamine during the current pregnancy with 71% receiving optimal (at least 3 doses) doses of sulphadoxine pyrimethamine for intermittent preventive treatment of malaria in pregnancy at the time of study. The study revealed that women who attended ANC ≥4 times (Adjusted OR = 4.7, 95% CI 1.31-17.2), knowledge of malaria in pregnancy (Adjusted OR = 2.2, 95% CI 1.03-4.62) and knowledge of intermittent preventive treatment for malaria in pregnancy (Adjusted OR = 1.8, 95% CI 1.15-2.96) were found to be positively associated with the uptake of optimal doses of sulphadoxine pyrimethamine.

CONCLUSION

This study has demonstrated that having a good knowledge of malaria in pregnancy and intermittent preventive treatment of malaria in pregnancy can significantly influence the uptake of optimal doses of sulphadoxine pyrimethamine. Encouraging women to attend antenatal care regularly (at least four visits) could also increase the optimal uptake of sulphadoxine pyrimethamine.

摘要

引言

疟疾在加纳仍然是一个公共卫生挑战,尤其是在孕妇中。加纳采用了使用周效磺胺-乙胺嘧啶进行孕期疟疾间歇性预防治疗的政策。尽管该政策已实施,但其覆盖率仍然很低。本研究旨在调查影响在苏尼亚尼市进行孕期疟疾间歇性预防治疗接受率的因素。

方法

这是一项采用定量方法的横断面研究。该研究于2015年1月至6月期间在苏尼亚尼市的五个选定机构进行。对从选定卫生机构的产前诊所随机抽取的400名孕妇进行了结构化问卷调查。使用Stata12对定量数据进行描述性、双变量和多变量分析。

结果

共研究了400名孕周为36周或以上的孕妇。研究表明,98.5%的孕妇在本次妊娠期间接受了至少一剂周效磺胺-乙胺嘧啶,71%的孕妇在研究时接受了最佳剂量(至少3剂)的周效磺胺-乙胺嘧啶用于孕期疟疾间歇性预防治疗。研究表明,参加产前检查≥4次的妇女(调整后的比值比=4.7,95%置信区间1.31-17.2)、孕期疟疾知识(调整后的比值比=2.2,95%置信区间1.03-4.62)和孕期疟疾间歇性预防治疗知识(调整后的比值比=1.8,95%置信区间1.15-2.96)与最佳剂量周效磺胺-乙胺嘧啶的接受率呈正相关。

结论

本研究表明,对孕期疟疾和孕期疟疾间歇性预防治疗有良好的了解可显著影响最佳剂量周效磺胺-乙胺嘧啶的接受率。鼓励妇女定期参加产前保健(至少四次就诊)也可提高周效磺胺-乙胺嘧啶的最佳接受率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9403/5839217/f73328c8bb90/PAMJ-28-122-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验