加纳沃尔特地区采用磺胺多辛-乙胺嘧啶间歇性预防治疗疟疾的需求。
The demand for intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine in the Volta Region of Ghana.
机构信息
Department of Public Administration and Health Services Management, Business School, University of Ghana, Legon-Accra, Ghana.
Deparment of Health Policy Planning and Management, Fred N. Binka School of Public Health, University of Health and Allied Sciences, Ho, Ghana.
出版信息
PLoS One. 2024 Sep 5;19(9):e0308321. doi: 10.1371/journal.pone.0308321. eCollection 2024.
BACKGROUND
Malaria in pregnancy (MiP) is a preventable condition leading to maternal and neonatal morbidity and mortality. Invariably, with all the knowledge about the serious consequences of MiP for the woman, the unborn child, and the neonate, the uptake of Intermittent Preventive Treatment of Malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) is low in most malaria-endemic countries, including Ghana. This study sought to examine the uptake and service user predictors of the implementation of IPTp-SP after the policy upgrade in 2014.
METHODS
This cross-sectional survey was carried out in two selected districts in the Volta Region. The study participants were randomly selected from communities within Nkwanta North and North Tongu District. A total of 438 mothers who have delivered in the past 24 months were selected for the study. The women were interviewed on their background, knowledge, and attitude toward the use of IPTp-SP using a structured questionnaire. Multiple logistic regression was done to determine the factors that influence the demand for IPTp-SP. The results were presented in the form of tables.
RESULTS
The mean number of antenatal care (ANC) attendance was 5 (SD:2.6) visits per client, with 262 (59.82%) of them getting the 3+ doses of IPTp-SP. Also, a significant 44 (10.1%) of the mothers did not receive any dose of IPTp-SP. Respondents who attended antenatal clinics 4-7 times had 7 (CI:3.9-12.3) times higher uptake of 3+ doses of IPTp-SP as compared to others who attended less than 4 visits. Similarly, women who had 8 or more visits had a 16.1 (CI: 5.9-43.6) times higher chance of getting more than 2 doses of IPTp-SP compared with others who had fewer than 4 attendances.
CONCLUSION
The uptake of 3+ doses of IPTp-SP is still lower than the global target of 80%. Thus, the need for innovative interventions aimed at improving antenatal attendance and early booking for IPTp-SP are recommended.
背景
妊娠疟疾（MiP）是一种可预防的疾病，可导致孕产妇和新生儿发病率和死亡率。尽管人们对 MiP 对妇女、未出生婴儿和新生儿的严重后果有了全面的认识，但在包括加纳在内的大多数疟疾流行国家，间歇性预防治疗疟疾采用磺胺多辛-乙胺嘧啶（IPTp-SP）的接种率仍然很低。本研究旨在检查 2014 年政策升级后，实施 IPTp-SP 的接种率和服务使用者的预测因素。
方法
本横断面调查在沃尔特地区的两个选定地区进行。研究参与者是从 Nkwanta North 和 North Tongu 区的社区中随机选择的。共有 438 名在过去 24 个月内分娩的母亲被选入研究。对这些妇女进行了关于其背景、知识和对使用 IPTp-SP 的态度的访谈，使用了结构化问卷。采用多因素逻辑回归分析来确定影响对 IPTp-SP 的需求的因素。结果以表格形式呈现。
结果
每位产妇的平均产前护理（ANC）就诊次数为 5（SD：2.6）次，其中 262（59.82%）人接受了 3 剂以上的 IPTp-SP。此外，有 44（10.1%）名母亲没有接受任何剂量的 IPTp-SP。与接受少于 4 次就诊的人相比，接受 4-7 次 ANC 就诊的受访者接受 3 剂以上剂量的 IPTp-SP 的可能性高 7（CI：3.9-12.3）倍。同样，与接受少于 4 次就诊的人相比，接受 8 次或更多次就诊的妇女接受 2 剂以上 IPTp-SP 的几率高 16.1（CI：5.9-43.6）倍。
结论
接受 3 剂以上剂量的 IPTp-SP 的接种率仍然低于全球 80%的目标。因此，建议采取创新干预措施，旨在提高产前就诊率和早期登记接受 IPTp-SP。
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