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在伊朗的苯丙胺使用者中未发现亚组证据。

No evidence of subgroups found in amphetamine consumers in Iran.

作者信息

Bananej Atireza, Völkl-Kernstock Sabine, Lesch Otto, Walter Henriette, Skala Katrin

机构信息

Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

Department of Child and Adolescent Psychiatry, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

出版信息

Neuropsychiatr. 2018 Jun;32(2):69-74. doi: 10.1007/s40211-018-0259-0. Epub 2018 Mar 7.

DOI:10.1007/s40211-018-0259-0
PMID:29516360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5993840/
Abstract

Amphetamine type substances are the second most commonly consumed illicit drug type and their use is an important contributor to the global burden of disease. This investigation set out to determine whether, similar to alcohol or nicotine addiction, subgroups of consumers can also be found in amphetamine addicts. 204 consumers of methamphetamine only (n = 50) or both methamphetamine and heroin (n = 154) have been investigated in Mashhad, Iran by means of "Lesch Alcoholism Typology". No significant differences in consumption pattern or age of onset have been found between the different types. Many subjects, however, reported symptoms of anxiety (n=78) or depression (n = 129) prior to drug use. These findings highlight the need for high quality epidemiological studies further addressing this issue.

摘要

苯丙胺类物质是第二大最常被使用的非法药物类型,其使用是全球疾病负担的一个重要因素。本调查旨在确定,与酒精或尼古丁成瘾情况类似,在苯丙胺成瘾者中是否也能发现不同的消费亚组。在伊朗马什哈德,通过“莱施酒精中毒类型学”方法对204名仅使用甲基苯丙胺(n = 50)或同时使用甲基苯丙胺和海洛因(n = 154)的使用者进行了调查。不同类型之间在消费模式或开始使用的年龄方面未发现显著差异。然而,许多受试者报告在使用药物之前有焦虑症状(n = 78)或抑郁症状(n = 129)。这些发现凸显了开展高质量流行病学研究以进一步解决这一问题的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cc8/5993840/56f82ce462ee/40211_2018_259_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cc8/5993840/56f82ce462ee/40211_2018_259_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cc8/5993840/56f82ce462ee/40211_2018_259_Fig1_HTML.jpg

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本文引用的文献

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Use of amphetamine-type stimulants in the Islamic Republic of Iran, 2004-2015: a review.2004 - 2015年伊朗伊斯兰共和国苯丙胺类兴奋剂的使用情况综述
East Mediterr Health J. 2017 May 1;23(3):245-256. doi: 10.26719/2017.23.3.245.
2
Pharmacotherapeutic agents in the treatment of methamphetamine dependence.治疗甲基苯丙胺成瘾的药物治疗剂。
Expert Opin Investig Drugs. 2017 May;26(5):563-578. doi: 10.1080/13543784.2017.1313229. Epub 2017 Apr 7.
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The profile of psychiatric symptoms exacerbated by methamphetamine use.使用甲基苯丙胺加剧的精神症状概况。
Drug Alcohol Depend. 2016 Apr 1;161:104-9. doi: 10.1016/j.drugalcdep.2016.01.018. Epub 2016 Jan 30.
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Global burden of disease attributable to illicit drug use and dependence: findings from the Global Burden of Disease Study 2010.全球疾病负担归因于非法药物使用和依赖的情况:来自 2010 年全球疾病负担研究的结果。
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