非诺特罗与异丙托溴铵定量气雾剂联合使用引起支气管扩张的临床研究。
Clinical study on bronchodilation induced by a metered aerosol of fenoterol in combination with ipratropium bromide.
作者信息
Bisetti A, Guerzoni P, Cavalieri C, Moretti M, Marchioni C F
出版信息
Respiration. 1986;50 Suppl 2:160-4. doi: 10.1159/000195118.
The response to an aerosol preparation containing 100 micrograms fenoterol and 40 micrograms ipratropium bromide per puff (Duovent) was compared with a placebo in 18 asthmatic patients in a double-blind cross-over fashion. We measured changes in lung function tests and pulse rate. Duovent induced a significant improvement in lung tests with statistical relevance for VEMS and Raw in comparison with placebo. The combination of fenoterol and ipratropium bromide also provided a long-lasting bronchodilatation without side effects.
以双盲交叉方式，对18名哮喘患者使用每喷含100微克非诺特罗和40微克异丙托溴铵的气雾剂制剂（多索茶碱）与安慰剂进行了比较。我们测量了肺功能测试和脉搏率的变化。与安慰剂相比，多索茶碱使肺功能测试有显著改善，对最大呼气中期流速（VEMS）和气道阻力（Raw）具有统计学意义。非诺特罗和异丙托溴铵的组合还提供了持久的支气管扩张作用且无副作用。
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