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在哮喘治疗中，对单剂量定量吸入器（Duovent，异丙托溴铵加非诺特罗组合制剂）与沙丁胺醇进行比较。

A comparison between a combination of ipratropium bromide plus fenoterol in a single metered dose inhaler (Duovent) and salbutamol in asthma.

作者信息

Flint K C, Hockley B, Johnson N M

出版信息

Postgrad Med J. 1983 Nov;59(697):724-5. doi: 10.1136/pgmj.59.697.724.

DOI:10.1136/pgmj.59.697.724
PMID:6227877
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2417671/
Abstract

The efficacy of a single metered dose inhaler containing a combination of fenoterol (100 micrograms/puff) and ipratropium bromide (40 micrograms/puff) has been assessed in 12 asthmatics. We conclude that the bronchodilator effect of 2 puffs of the combination inhaler was significantly greater than that achieved by 2 puffs of salbutamol (100 micrograms/puff).

摘要

对12名哮喘患者评估了含有非诺特罗（每喷100微克）和异丙托溴铵（每喷40微克）组合的单剂量定量吸入器的疗效。我们得出结论，该组合吸入器2喷的支气管扩张作用明显大于沙丁胺醇（每喷100微克）2喷所达到的作用。

相似文献

1
A comparison between a combination of ipratropium bromide plus fenoterol in a single metered dose inhaler (Duovent) and salbutamol in asthma.在哮喘治疗中，对单剂量定量吸入器（Duovent，异丙托溴铵加非诺特罗组合制剂）与沙丁胺醇进行比较。
Postgrad Med J. 1983 Nov;59(697):724-5. doi: 10.1136/pgmj.59.697.724.
2
Salbutamol versus Duovent (a combination of fenoterol and ipratropium bromide) in asthma.沙丁胺醇与多索茶碱（非诺特罗与异丙托溴铵的复方制剂）治疗哮喘的对比
Eur J Respir Dis Suppl. 1983;128 (Pt 2):548-50.
3
A comparison of effects of inhaling a combined preparation of fenoterol with ipratropium bromide (Duovent) with those of fenoterol and salbutamol.吸入非诺特罗与异丙托溴铵复方制剂（多索茶碱）与吸入非诺特罗和沙丁胺醇的效果比较。
Postgrad Med J. 1984;60 Suppl 1:24-7.
4
[Clinical pharmacological trials of a new metered dose inhaler, IK-6, a combination of the bronchodilators fenoterol and ipratropium bromide (author's transl)].新型定量吸入器IK-6（支气管扩张剂非诺特罗与异丙托溴铵的复方制剂）的临床药理试验（作者译）
Wien Med Wochenschr. 1980 Jun 15;130(11):385-93.
5
A dose response study comparing Duovent vs salbutamol.
N Z Med J. 1987 Dec 9;100(837):742-4.
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Comparison of Duovent and salbutamol inhalers in chronic stable asthma.慢性稳定型哮喘中Duovent与沙丁胺醇吸入器的比较。
Postgrad Med J. 1984;60 Suppl 1:28-31.
7
[Controlled clinical study of the effects of a single aerosol administration of a fenoterol-ipratropium bromide combination in comparison with salbutamol].[与沙丁胺醇相比，非诺特罗-异丙托溴铵联合气雾剂单次给药效果的对照临床研究]
Arch Monaldi. 1983 Sep-Dec;38(5-6):241-54.
8
Comparison of a combination of fenoterol with ipratropium bromide (Duovent) and salbutamol in young adults with nocturnal asthma.非诺特罗与异丙托溴铵联合制剂（多爱喘）和沙丁胺醇对年轻成年夜间哮喘患者疗效的比较
Respiration. 1989;55(3):152-7. doi: 10.1159/000195726.
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Clinical physiological data on the bronchodilator effect of Duovent versus salbutamol in chronic obstructive lung disease.
Respiration. 1986;50 Suppl 2:165-8. doi: 10.1159/000195119.
10
Protective effect of Duovent on bronchospasm induced by carbachol in comparison with each of its components.
Respiration. 1986;50 Suppl 2:152-4. doi: 10.1159/000195116.

引用本文的文献

1
Anticholinergic agents for chronic asthma in adults.用于成人慢性哮喘的抗胆碱能药物。
Cochrane Database Syst Rev. 2004;2004(3):CD003269. doi: 10.1002/14651858.CD003269.pub2.
2
Salbutamol in the 1980s. A reappraisal of its clinical efficacy.20世纪80年代的沙丁胺醇。对其临床疗效的重新评估。
Drugs. 1989 Jul;38(1):77-122. doi: 10.2165/00003495-198938010-00004.
3
Ipratropium bromide: are patients treated with optimal therapy?异丙托溴铵：患者接受的是最佳治疗吗？
Postgrad Med J. 1990 Dec;66(782):1040-2. doi: 10.1136/pgmj.66.782.1040.

本文引用的文献

1
Comparative trial of a new anticholinergic bronchodilator, Sch 1000, and salbutamol in chronic bronchitis.新型抗胆碱能支气管扩张剂Sch 1000与沙丁胺醇治疗慢性支气管炎的对比试验
Br Med J. 1973 Oct 20;4(5885):134-6. doi: 10.1136/bmj.4.5885.134.
2
Comparison of aerosol ipratropium bromide and salbutamol in chronic bronchitis and asthma.异丙托溴铵气雾剂与沙丁胺醇在慢性支气管炎和哮喘中的比较
Br Med J. 1975 Feb 22;1(5955):430-2. doi: 10.1136/bmj.1.5955.430.
3
Combined cholinergic antagonist and beta 2-adrenoceptor agonist bronchodilator therapy by inhalation.
Aust N Z J Med. 1979 Oct;9(5):511-4. doi: 10.1111/j.1445-5994.1979.tb03386.x.
4
Bronchodilatation and the site of airway resistance in severe chronic bronchitis.重度慢性支气管炎中的支气管扩张及气道阻力部位
Thorax. 1979 Feb;34(1):51-6. doi: 10.1136/thx.34.1.51.